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Articles by C. Zongo
Total Records ( 4 ) for C. Zongo
  C. Zongo , Etienne-Francois O. Akomo , A. Savadogo , Louis Clement Obame , Jean Koudou and Alfred S. Traore
  The antimicrobial activity of the total alkaloids from the leaves of Mitragyna inermis (Willd.) O. Kuntze (Rubiaceae) From Burkina Faso was evaluated using disc diffusion essay and broth microdilution assay. The extract was used against ten (10) reference bacterial strains and three (3) clinical isolates including Gram(+) and Gram(-) strains. The alkaloids showed moderate activity against mcroorganisms tested. The highest Diameter of Inhibition Zone (DIZ) was obtained with S. aureus ATCC9244 (23 ± 1 mm). The lowest Minimum Inhibitory Concentration (MIC) obtained was 0.625 mg mL-1 recorded with three (3) Gram(+) bacteria (S. aureus ATCC 25293, S. aureus (clinical isolate) and S. carmorum LMG 13567) and one Gram(-) strain (P. mirabilis CIP104588. Results showed that Gram(+) bacteria are more sensitive to alkaloids from M. inermis than Gram(-) bacteria. This study confirmed the use of the plant in traditional medicine against some infectious diseases.
  C. Zongo , A. Savadogo , L. Ouattara , I.H.N. Bassole , C.A.T. Ouattara , A.S. Ouattara , N. Barro , J. Koudou and A.S. Traore
  The main goal of this study was to determine the phenol content, the antimicrobial and the antioxidant activities of acetone and water extracts from the rhizomes of Ampelocissus grantii (Baker) Planch (Vitaceae). The polyphenol content of extracts was determined colorimetrically using Folin-Ciocalteu method. The antioxidant activity of the same extracts was also screened using 1, 1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging method. The antimicrobial activity was performed by disc diffusion and broth microdilution assays against 9 reference bacterial strains including gram-negative and gram-positive bacteria and 1 fungal strain. The acetone extract exhibited the higher level of Total Polyphenol Contents (TPC) which correlated with strong antioxidant activity (IC50 = 10.87 μg mL-1 and AAI = 5.6) and antimicrobial activity. The polyphenol content of the acetone extract was 124.26 gallic acid equivalent/100 g (GAE/100 g), that of water extract was 74.25 GAE/100 g. The largest diameter of inhibition zone (DIZ) (15 mm) and the lowest Minimal Inhibitory Concentration (MIC) value (0.625 mg mL-1) were recorded with Enterococcus faecalis 10907 CIP and Bacillus subtilus ATCC 21332. This study is a scientific base on the use of this plant in traditional health cure system.
  L. Ouattara , J. Koudou , C. Zongo , N. Barro , A. Savadogo , I.H.N. Bassole , A.S. Ouattara and Alfred S. Traore
  The main goal of this study was to determine the phenol content, the antibacterial and the antioxidant activities of the three species of Lannea largely use in traditional medicine in Burkina Faso. The total phenolic and flavonoid contents of hydro alcoholic extract (70%V/V ethanol/distilled water) from the barks of Lannea acida, Lannea microcarpa and Lannea velutina (Anacardiaceae) were determined by the method of Folin Ciocalteu and AlCl3 by spectrophotometry. These extracts were tested for their antioxidant and antibacterial activities. Antioxidant activity was determined by the method of DPPH and compared with quercetin. Antibacterial activity was performed by disk diffusion and broth microdilution essays against nine reference bacterial strains including gram-positive and gram-negative bacteria. L.acida exhibited the highest total phenolic contents (40.55±0.26 g GAE/100 g) which correlated with better antioxidant activity (IC50 = 345.72±7.76 μg mL-1). Furthermore the highest content of total flavonoids (11.02±0.04 g QE/100 g) and the largest anti bacterial spectrum (7.82 μg mL-1≤MIC≤ 62.5 μg mL-1) were recorded with L.velutina. These results show that the barks of L. acida and L.velutina could be used respectively as a potential natural antioxidant and antibacterial agent.
  E.F.O. Akomo , C. Zongo , S.D. Karou , L.C. Obame , A. Savadogo , C. Atteke and A.S. Traore
  Because of the resistance of pathogens to actually available drugs, there is a continuous need for new agents to cure several diseases such as malaria and microbial infections. In the establishment of new drugs, plant are often a source of new leads, indeed aqueous, acetone and methanol extracts of Canthium multiflorum were tested for antiplasmodial and antibacterial activities. The antiplasmodial activity was performed on fresh clinical strains of Plasmodium falciparum using light microscopy. The results revealed that the methanol extract was the most active with IC50 of 4.69 μg mL-1. The NCCLS microdilution method performed on clinical and reference strains of pathogenic bacteria yielded MIC and MBC values ranging from 312 to 1250 and 625 to 2500 μg mL-1, respectively. The qualitative analysis of the extract revealed the presence of several chemical groups such as alkaloids, terpens and tannins that might be responsible for the activity of the plant. The issue of this study showed that C. multiflorum is a plant that many attention should be paid to because of it pharmacological potentials.
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