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Articles
by
C. Bisseye |
Total Records (
5 ) for
C. Bisseye |
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D. Ilboudo
,
J. Simpore
,
D.S. Sanou
,
D. Karou
,
D.J. Sia
,
D. Ouermi
,
C. Bisseye
,
T. Sagna
,
S. Odolini
,
F. Buelli
,
V. Pietra
,
S. Pignatelli
,
C. Gnoula
,
J.B. Nikiema
and
F. Castelli
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In Sub-Saharan Africa, many HIV infected people are co-infected with Human Herpes Virus 8 (HHV-8). Therefore, the present study aimed to: (1) identify the pregnant women co-infected by HIV and HHV-8 at Saint Camille Medical Centre; (2) use three molecules (Zidovudine, Nevirapine and Lamivudine) to interrupt the vertical transmission of HIV and (3) use the PCR technique to diagnose children, who were infected by these viruses, in order to offer them an early medical assistance. A total of 107 pregnant women, aged from 19 to 42 years were diagnosed to be HIV positive at Saint Camille Centre; among them 13 were co-infected with HHV-8. All included women received the HAART. Two to six months after childbirth their babies underwent PCR diagnosis for HIV and HHV-8. The results revealed that, among these mothers, 68.2% were housewives, 34.6% were illiterates and 60.7% did not have university degree. The prevalence of HHV-8 among these pregnant women was 12.15% and the rate of vertical transmission of both HIV and HHV-8, was 0.0%. The issue of this study revealed that the antiretroviral therapy increased the mother CD4 T-cells, prevented the transcription of the mRNA of HHV-8 and blocked HIV vertical transmission. |
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D. Ouermi
,
J. Simpore
,
A.M.G. Belem
,
D. S. Sanou
,
D.S. Karou
,
D. Ilboudo
,
C. Bisseye
,
S.M. Onadja
,
V. Pietra
,
S. Pignatelli
,
C. Gnoula
,
J.B. Nikiema
and
G.B. Kabre
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Toxoplasma gondii infections can induce serious complications in HIV-infected pregnant women, leading to miscarriage; favour the mother-to-child transmission of HBV and HIV and birth defects. The purposes of this study were: (1) to quantify IgM and IgG antibodies to Toxoplasma gondii in HIV-seropositive and seronegative pregnant women, (2) to identify hepatitis B antigens (HBsAg) in pregnant women and (3) to determine T. gondii and HBV co-infections among these patients. The study was conducted at Centre Medical Saint Camille, in Burkina Faso from January to June 2009. A total of 276 HIV-infected and uninfected pregnant women were included. All women had less than 32 weeks of amenorrhoea and were aged from 19 to 42 years. Toxoplasma gondii antibodies and HBsAg were detected using ELISA method. In addition, women freely agreed to answer a questionnaire. The results of our investigations revealed that, among these pregnant women, 38.8% were illiterates, 50.4% were housewives and only 5.4% were civil servants. Positive T. gondii-specific IgM (4.7%) and IgG (27.2%) were detected. In this study, we found that HIV-seropositive status seem to be associated with great prevalence rates of both T. gondii (31.9 vs. 22.5%) and HBV (13.0 vs. 5.8%). The elevated co-infection rate in HIV-positive women suggested that they are exposed to T. gondii and HBV infections prevalently because of their immune depression. Therefore, to reduce the prevalence of T. gondii and HBV among HIV-seropositive pregnant women, lamivudine could be included in their HEART and women should follow healthy lifestyle formation. |
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T. Sagna
,
F. Djigma
,
M. Zeba
,
C. Bisseye
,
S.D. Karou
,
D. Ouermi
,
V. Pietra
,
C. Gnoula
,
K. Sanogo
,
J.B. Nikiema
and
J. Simpore
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The vaginal swabs among HIV-positive women in Africa often revealed opportunistic infections such as human Papillomavirus (HPV) and Mycoplasma that induce respectively cervix cancer and diseases such as vaginosis, abortions, infertility in through salpingitis. The purposes of this study were to: (1) seek for, the prevalence of pathogens such as HPV and Mycoplasma; (2) characterize the strains of HPV and estimate their prevalence; (3) identify among these women, those who were co-infected by these pathogens in order to cure them. From February 2009 to January 2010, 156 HIV-positive women attending our medical centers and aged from 19-45 years (mean age 33.65±5.75 years) had voluntarily accepted vaginal specimens tests. PCR, ELISA and molecular hybridization were used for the identification and characterization of these pathogens. The results revealed the presence of Mycoplasma and HPV in 25.64 and 58.33% cases, respectively. The following HPV genotypes and the following prevalence were recorded: HPV-50'S (24.11%), HPV-18 (21.28%), HPV-30'S (18.44%) and HPV-16 (5.67%). The study also enable the identification of co-infections such as HPV-18 strains with HPV-30'S (5.67%) and HPV-30'S with HPV-50'S (3.55%). Other germs infecting the female genital tract including Candida albicans (20.51%), Escherichia coli (12.18%), Treponema pallidum (3.85%), Streptococcus agalactiae (3.21%) and Staphylococcus aureus (1.92%) were isolated. This preliminary research work showed the incidence of several genital pathogens, this could be a springboard for nationwide epidemiological study on HPV strains circulating in Burkina Faso. |
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M.T.A. Zeba
,
C.A.T. Ouattara
,
S.D. Karou
,
C. Bisseye
,
D. Ouermi
,
F.W. Djigma
,
T. Sagna
,
V. Pietra
,
R. Moret
,
J. Nikiema
and
J. Simpore
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HCV and HBV cause annually, 2000 deaths from liver cancer
in Burkina Faso. In this country, serological screening of hepatitis viruses
B and C is only systematic among blood donors. The aims of this study were;
(1) to investigate the reasons for the prescription of the screening for hepatitis
B and C; (2) to determine HCV and HBV prevalence among 462 patients attending
the Saint Camille Centre and (3) to identify patients with acute hepatitis or
with chronic hepatitis for better monitoring. From February to May 2012, 462
patients attending the laboratory of the Saint Camille Medical Centre with viral
hepatitis suspicion were screened. The hepatitis B and C serological markers
were detected through Enzyme Immuno Assay (EIA) technique using commercial reagent
kits. The clinical symptoms were also recorded for each patient. The results
revealed that, the main clinical symptoms that prompted physicians to request
HBV and HCV screenings were: asthenia (39.4%), anorexia (21.2%), abdominal pains
(19.0%), nausea (10.4%), others (10.0%). The prevalence of HbsAg was 29.4% among
the screened people. Patients with acute hepatitis B, active chronic hepatitis
B and non-active chronic hepatitis B represented 11.2, 2.2 and 16.0%, respectively.
The acquisition of immunity against HBV after vaccination was attempted for
11.7% people. HCV prevalence was 3.9% and its coinfection with HBV was 2.2%.
This study showed a high prevalence for hepatitis B and C among patients attending
Saint Camille Medical Centre. Without hygiene education and HBV/HCV prevention,
viral hepatitis infection will become a serious public health problem in Burkina
Faso. |
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M. Sanou
,
S.T. Soubeiga
,
F. Bationo
,
T.R. Compaore
,
T.M. Zohoncon
,
G.N. Diatto
,
P. Ouedraogo
,
V. Pietra
,
B.M. Nagalo
,
C. Bisseye
,
R. Ouedraogo Traore
and
J. Simpore
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Although, HIV-2 is generally less pathogenic than HIV-1 and
its progression towards AIDS occurs less frequently. HIV-2 remains an important
cause of disease in West Africa. This study aimed to evaluate HIV-1 and HIV-2
prevalence among pregnant women and to describe the demographic and clinical
profile of patients with HIV-2 infection from 2003-2013 at St Camille and General
Lamizana Military Medical Centers. A retrospective investigation was conducted
using 12,287 medical records from patients screened for HIV. To respond to the
lack of data available regarding HIV-2 treatment and also to address the approach
to clinical, biological as well as therapeutic monitoring, 62 HIV-2 infected
patients medical records were
studied. Seroprevalence of 10.6 and 0.14% were obtained, respectively for HIV-1
and HIV-2 among 12,287 women screened during the study period. From the sixty
two (62) HIV-2 patients, the average age was 49.2 years (sex ratio was 0.65).
The weight loss and diarrhea were the major clinical manifestations observed,
respectively 54.8 and 25.8%. Fungi and herpes zoster (shingles) infections were
reported as major opportunistic infections. Also, nearly half of the patients
had more than 60 kg, less than 2% were in WHO stage IV and about 2/3 had a CD4
count bellow 250 cells mm-3. AZT-3TC-IDV/LPV/R was the most prescribed
combination. The gain in weight gain the Body Mass Index (BMI) improvement and
the non-significant increase of the rate of CD4 between 1st (M1) and 24th month
(M24) were observed after treatment with antiviral. |
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