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| Articles
by
C. Balachandran |
Total Records (
5 ) for
C. Balachandran |
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S. Subapriya
,
S. Vairamuthu
,
B. Murali Manohar
and
C. Balachandran
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Thiram a fungicide used for treating corn and storing
food grains were incorporated at 15, 30 and 60 ppm into the toxin free
diet of broiler chicken for four weeks from the day of hatch. The clinical
signs of tibial dyschondroplasia like reduced weight gain, lameness,
abnormal bending of the tibial bones, enlarged hock joints and sternal
recumbency were observed. The birds were sacrificed at the end of second
and fourth week. Blood samples were collected for estimation of
hematological parameters and sera separated for biochemical analysis. The
packed cell volume and hemoglobin values were unaltered. Serum total
proteins, albumin, globulin, albumin:globulin ratio, aspartate amino
transferase, alanine amino transferase, alkaline phosphatase, gamma
glutamyl transferase were unaltered. Hypercholesterolemia was observed in
all the thiram fed birds and hypocalcemia and hypophosphatemia in the 60
ppm thiram fed birds. |
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S. Subapriya
,
S. Vairamuthu
,
B. Murali Manohar
and
C. Balachandran
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An investigation was undertaken to study the body weight
gain and feed conversion efficiency in broiler chicken fed with thiram a
fungicide used for treating corn and storing food grains. Forty eight
birds were randomly distributed into four groups of twelve each and thiram
was incorporated at 15, 30 and 60 ppm into the toxin free diet for four
weeks from the day of hatch. Blood samples were collected, sera separated
and HI titres were measured in the control and treated sera. Birds were
sacrificed at the end of second and fourth week for detailed examination
of lymphoid organs. There was a significant reduction in the antibody
titre in the thiram fed birds. Lymphocyte proliferation assay conducted
from the lymphocytes prepared from the spleen showed significant reduction
in the stimulation index. Histopathology of the lymphoid organs including
bursa, spleen thymus and caecal tonsils showed lymphoid depletion to
lymphocytolysis. |
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S. Subapriya
,
S. Vairamuthu
,
B. Murali Manohar
and
C. Balachandran
|
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Thiram a fungicide used for treating corn and storing
food grains were incorporated at 15, 30 and 60 ppm into the toxin free
diet of broiler chicken for four weeks from the day of hatch. Body weights
(g) were recorded at weekly intervals. Average weekly feed consumption (g)
and conversion were arrived at. The results showed that feeding thiram
caused dose and time related severe depression in the body weight gain.
Significant reduction in weight gain was observed from the first week in
60 ppm level and from second week in 30 ppm level. By fourth week all the
thiram fed birds showed significant reduction in the weight gain. |
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S. Subapriya
,
S. Vairamuthu
,
B. Murali Manohar
and
C. Balachandran
|
| |
Thiram a fungicide used for treating corn and for storing
food grains were incorporated at 15, 30 and 60 ppm into the toxin free
diet of broiler chicken for four weeks from the day of hatch. The clinical
signs were reduced weight gain, lameness, abnormal bending of the tibial
bones, enlarged hock joints and sternal recumbency. Grossly tibial
dyschondroplasia was seen as a white opaque unmineralized cartilage plug
in the tibiotarsus. Histopathologically, tibiotarsus revealed thinning of
the growth plate, irregular arrangement of the proliferating layer,
abnormal thickening of the transitional layer and thickened hypertrophic
layer in the thiram fed groups. Changes were also seen in the liver, bile
duct, kidney, heart, crop, gizzard, intestine, lymphoid organs including
bursa, spleen and caecal tonsils and brain. There was no mortality at any
levels of thiram tested. Results of the present study thus revealed that
thiram at a level of even 15 ppm affected the health and performance of
broiler chicken. |
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R Rao
and
C. Balachandran
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Stigma is almost synonymous with visible deformity and this is what makes leprosy a dreaded disease for the common man. Deformities in children are more distressing, due to the limitation of their physical, academic and social life. An 11-year-old female child was presented with trophic ulceration of right foot and triple nerve paralysis (i.e. total claw hand with wrist drop) of the left hand of 2 years duration. In addition, she had multiple hypopigmented hypoaesthetic patches on the extremities and buttocks. She was diagnosed as a case of borderline tuberculoid leprosy and was started on WHO MB MDT therapy. Leprosy in children is an indicator for disease prevalence in general population and occurrence of deformities points towards the delay in making the diagnosis and the stigma associated with the disease. |
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