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Articles by C. Balachandran
Total Records ( 5 ) for C. Balachandran
  S. Subapriya , S. Vairamuthu , B. Murali Manohar and C. Balachandran
  Thiram a fungicide used for treating corn and storing food grains were incorporated at 15, 30 and 60 ppm into the toxin free diet of broiler chicken for four weeks from the day of hatch. The clinical signs of tibial dyschondroplasia like reduced weight gain, lameness, abnormal bending of the tibial bones, enlarged hock joints and sternal recumbency were observed. The birds were sacrificed at the end of second and fourth week. Blood samples were collected for estimation of hematological parameters and sera separated for biochemical analysis. The packed cell volume and hemoglobin values were unaltered. Serum total proteins, albumin, globulin, albumin:globulin ratio, aspartate amino transferase, alanine amino transferase, alkaline phosphatase, gamma glutamyl transferase were unaltered. Hypercholesterolemia was observed in all the thiram fed birds and hypocalcemia and hypophosphatemia in the 60 ppm thiram fed birds.
  S. Subapriya , S. Vairamuthu , B. Murali Manohar and C. Balachandran
  An investigation was undertaken to study the body weight gain and feed conversion efficiency in broiler chicken fed with thiram a fungicide used for treating corn and storing food grains. Forty eight birds were randomly distributed into four groups of twelve each and thiram was incorporated at 15, 30 and 60 ppm into the toxin free diet for four weeks from the day of hatch. Blood samples were collected, sera separated and HI titres were measured in the control and treated sera. Birds were sacrificed at the end of second and fourth week for detailed examination of lymphoid organs. There was a significant reduction in the antibody titre in the thiram fed birds. Lymphocyte proliferation assay conducted from the lymphocytes prepared from the spleen showed significant reduction in the stimulation index. Histopathology of the lymphoid organs including bursa, spleen thymus and caecal tonsils showed lymphoid depletion to lymphocytolysis.
  S. Subapriya , S. Vairamuthu , B. Murali Manohar and C. Balachandran
  Thiram a fungicide used for treating corn and storing food grains were incorporated at 15, 30 and 60 ppm into the toxin free diet of broiler chicken for four weeks from the day of hatch. Body weights (g) were recorded at weekly intervals. Average weekly feed consumption (g) and conversion were arrived at. The results showed that feeding thiram caused dose and time related severe depression in the body weight gain. Significant reduction in weight gain was observed from the first week in 60 ppm level and from second week in 30 ppm level. By fourth week all the thiram fed birds showed significant reduction in the weight gain.
  S. Subapriya , S. Vairamuthu , B. Murali Manohar and C. Balachandran
  Thiram a fungicide used for treating corn and for storing food grains were incorporated at 15, 30 and 60 ppm into the toxin free diet of broiler chicken for four weeks from the day of hatch. The clinical signs were reduced weight gain, lameness, abnormal bending of the tibial bones, enlarged hock joints and sternal recumbency. Grossly tibial dyschondroplasia was seen as a white opaque unmineralized cartilage plug in the tibiotarsus. Histopathologically, tibiotarsus revealed thinning of the growth plate, irregular arrangement of the proliferating layer, abnormal thickening of the transitional layer and thickened hypertrophic layer in the thiram fed groups. Changes were also seen in the liver, bile duct, kidney, heart, crop, gizzard, intestine, lymphoid organs including bursa, spleen and caecal tonsils and brain. There was no mortality at any levels of thiram tested. Results of the present study thus revealed that thiram at a level of even 15 ppm affected the health and performance of broiler chicken.
  R Rao and C. Balachandran
 

Stigma is almost synonymous with visible deformity and this is what makes leprosy a dreaded disease for the common man. Deformities in children are more distressing, due to the limitation of their physical, academic and social life. An 11-year-old female child was presented with trophic ulceration of right foot and triple nerve paralysis (i.e. total claw hand with wrist drop) of the left hand of 2 years duration. In addition, she had multiple hypopigmented hypoaesthetic patches on the extremities and buttocks. She was diagnosed as a case of borderline tuberculoid leprosy and was started on WHO MB MDT therapy. Leprosy in children is an indicator for disease prevalence in general population and occurrence of deformities points towards the delay in making the diagnosis and the stigma associated with the disease.

 
 
 
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