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Articles by Basel Saleh
Total Records ( 1 ) for Basel Saleh
  Basel Saleh and Ayman Al-Mariri
  Background and Objective: Seaweed extracts displayed a broad spectrum as antimicrobial agent due to their richness in bioactive compounds. Seven seaweeds [Codium tomentosum (Chlorophyta), Corallina mediterranea, Hypnea musciformis and Laurencia papillosa (Rhodophyta) and Padina pavonica, Sargassum vulgare and Dictyota dichotoma (Phaeophyta)] crude extracts effectiveness had been evaluated against two fungal (Aspergillus niger and Candida albicans) strains using aqueous, methanol, ethanol, chloroform, acetone, ethyl acetate and hexane solvents. Materials and Methods: Seaweeds antifungal effect had been evaluated based on the zone of inhibition (ZI), Minimum Inhibitory Concentration (MIC) and Minimum Fungicidal Concentration (MFC). Amphotericin B (40 mg mL–1) was used as standard for antifungal activity. Results: Aqueous extracts showed no activity against the two tested fungi regardless examined seaweeds species. Whereas, the other six organic extracts adversely affected fungal strains. Overall, D. dichotoma showed no activity against the two tested fungi regardless examined solvents. Moreover, methanolic S. vulgare extract was the strongest by showing the lowest MIC value of 0.11 and 0.13 mg mL–1 against A. niger and C. albicans fungal strains, respectively and the lowest MFC value of 1.67 mg mL–1 for the both fungal strains. Conclusion: Seaweeds seem to be promising natural resources with low cost for antifungal treatment. Further researches on methanolic S. vulgare extracts fractions is requested.
 
 
 
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