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| Articles
by
Babak Mohammadi |
Total Records (
3 ) for
Babak Mohammadi |
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Ali Rezaie
,
Arash Pezeshki
,
Behzad Zadfattah
,
Mehrdad Nazeri
,
Changiz Ahmadizadeh
and
Babak Mohammadi
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Celandine with scientific name Chelidounium majus, spreads across the world and exists in Northern parts of Iran like Gilaan, the outskirts of Rasht, Roodbar and Mazandaran. Some of effective chemical compounds are: malic, copticine, cityicacid, chelerythrine, berberine, succinic acid and sangainarine acid. The herb’s other medical properties are: calmative, narcotic, anti spasm, lowering blood pressure, antibilious, cathartic and wormroot in internal uses. Epispastics and flesh wound amneliorator in external uses. Other chemical compounds of the herb have alkaloids that some of which are toxic those alkaloids are Chelidtine hemochelidotine, cheleritrine, sangainarine and protopine. In the present study, 30 Wistar male rats of 200-230 g weight and about 3 months old were used for laboratory experiments. Animals were kept in standard condition, at 20-25°C, 70% humidity and light cycle of 12 h lighting and 12 h darkness. Standard plates were used in order to feeding by method of ad-libitum, i.e., 24 h feeding. It can be concluded, generally that based on different studies the extract of celandine may affect via effecting on benzodiazepine receivers connected to GABA receivers (considering its flavonoid content). Based on the obtained results by the present study it can be said that according to sedation process the extract dosage of 400 mg kg-1 BW among other dosages has had more meaningful results and has a better sedation, pre-anesthetic and anti-anxiety effects compared with diazepam (p<0.01). |
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Ali Rezaie
,
Arash Pezeshki
,
Behzad Zadfattah
,
Mehrdad Nazeri
,
Changiz Ahmadizadeh
and
Babak Mohammadi
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Hempseed with scientific name Cannabis sativa, spreads across the world. Hempseed oil’s fatty acids compounds were obtained from different parts of Iran with different weather and were tested. The herb contains canabidole, canabinol and canabidiolic acid. The herb is used for preparing some sedation drugs which are used in neural stresses, anxiety, migraine, asthmatic coughs as well as local anesthesia in dentistry. Stuart points out that all parts of hempseed are used in China traditional medicine. Its seed is used as tonic, strengthening, laxative, diuretic, calmative, gastric anti parasite and narcotic. Masson and Teobold say that hempseed has a great value for tetanus treatment. Hempseed is a real calmative for stomachache and digestive disorders as well as beneficial for cancers, ulcers and rheumatic pains. In the present study, 30 Wistar male rats of 200-230 g weight and about 3 months old were used for laboratory experiments. Animals were kept in standard condition, at 20-25°C, 70% humidity and light cycle of 12 h lighting and 12 h darkness. Standard plates were used in order to feeding by method of ad libitum, i.e., 24 h feeding. Especial dishes were used for water. The rats were numbered in groups consisted of 5 animals and were placed in especial cages. |
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Ali Rezaie
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Babak Lotfollahi
,
Daryoush Mohajeri
,
Ghafour Mousavi
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Mehrdad Nazeri
,
Solmaz Zakhireh
and
Babak Mohammadi
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Acceleration in healing of surgical skin wounds, in order to reduction of post-operation consequences is most important. One of the most popular compounds used ever for skin care is lavender oil or Lavandula stoechas essential oil. The aim of this study was evaluate the healing effects of Lavandula stoechas extract in comparison with zinc oxide ointment on full thickness experimental open surgical skin wound healing in the rats. For this purpose, 75 female Wistar rats were randomly assigned in 5 groups of 15 animals each including: Control, treated by Eucerin as the placebo, treated by zinc oxide topical ointment and two remaining as test groups which received 10 and 20% Lavandula stoechas extracts. Under the general anesthesia and analgesia circumstances, a full thickness incisional open wound with 23 mm diameter was made on the skin of the back part of the rats. The healing process was studied macroscopically and microscopically at 0 (the day of surgery) 3, 7, 14, 21 and 28th days of experiment in all of the rats. The greatest degree of wound contraction was considered in Lavandula stoechas extract (10%) treated rats while this change was slighter in control group. In microscopic examination, the overall healing process of Lavandula stoechas extract (10%) treated rats was significantly better than the other experimental groups (p<0.05). The results obtained showed that Lavandula stoechas extract (10%) has more effective healing properties on full thickness open skin wounds compared to zinc oxide topical ointment. |
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