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Articles by B.Y. Muhammad
Total Records ( 2 ) for B.Y. Muhammad
  S.W. Hassan , R.A. Umar , M. Lawal , L.S. Bilbis , B.Y. Muhammad , U.Z. Faruk and A.A. Ebbo
  The alkaloidal composition, histopathological and toxicity studies of alkaloid and aqueous ethanol extracts of Boscia angustifolia on biochemical indices of kidney and liver functions in rats were studied. The amount of alkaloids detected in 50 g powdered root extract of the plant was 11.44% (w/v). Renal and liver indices were significantly (p<0.05) altered at higher doses of 703.60, 1125.70 (alkaloidal extract), 839.30 and 1342.80 mg kg-1 body weight (aqueous ethanol extract). The aqueous ethanol and alkaloidal root extracts produced histopathological lesions of the liver and kidney at higher doses. These lesions include perivascular cuffs, protein cast, infiltration (kidney) and slight infiltration and perivascular cuffs (liver). There was a significant (p<0.05) dose dependent decrease in weight in the rats given higher doses of the aqueous ethanol and alkaloidal root extracts of Boscia angustifolia. The use of this plant is associated with some levels of organ toxicity.
  S.O. Bello , B.Y. Muhammad , K.S. Gammaniel , I. Abdu-Aguye , H. Ahmed , C.H. Njoku and U.H, Salka
  The efficacy and tolerability of Solanum melongena and placebo in moderate to Severe asthmatics was evaluated in a randomized, single center, three-arm, triple blind placebo controlled trial in a tertiary hospital setting in Sokoto, Nigeria . The Main outcome measures were weekly disease severity score, daily Salbutamol (Ventolin) inhaler use. Weekly FEV 1 and PEF all expressed as % above baseline and PEF% predicted. Incidence of side effects was the secondary outcome measure. The study revealed significant improvement in all outcome measures over placebo in the two test arm but no significant difference between test arms. At the end of two weeks of daily intake, the dried fruit of Solanum melongena significantly improves asthma symptoms and signs and disease severity score and apparently have a salbutamol sparing effect. No adverse effect was noted.
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