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Articles by B.O. Bolaji
Total Records ( 3 ) for B.O. Bolaji
  A. Fadeyi , B.O. Bolaji , O.O. Oyedepo , O.O. Adesiyun , M.A.N. Adeboye , T.O. Olanrewaju , A. Aderibigbe , A.K. Salami , O.O. Desalu , A. Fowotade , C. Nwabuisi , A.A. Akanbi II , R.A. Raheem and A. Olalere
  Problem statement: Methicilin Resistant Staphylococcus Aureus (MRSA) Nosocomial Infection (NI) outbreaks and prevalence among various populations are well reported in literature particularly for developed countries. NI due to MRSA is a known cause of increased hospital stay, cost, morbidity and mortality especially among the critically ill. There is paucity of information on MRSA in developing nations including the carriage by critical healthcare givers who are potential transmitters. In most hospital in developing countries like Nigeria, there is neither surveillance system or control policy for MRSA. Approach: We screened healthcare workers in the critical care units of the University of Ilorin Teaching Hospital (UITH), Ilorin, Nigeria for MRSA and determined vancomycin susceptibility of the isolates. Swabs of both anterior nares and web spaces of the hands were taken, transported and incubated in Tween 80 at 35°C overnight aerobically before inoculation onto Mannitol Salt Agar (MSA). Inoculated MSA were incubated aerobically at 35°C for 18-24 h. Staphylococcus aureus was identified as Gram positive cocci with positive catalase, coagulase and DNAse test. MRSA were identified by combined oxacillin and cefoxitin discs diffusion method. Sensitivity to vancomycin was by vancomycin discs diffusion and vancomycin agar screen plating. Results: Of the 198 healthcare workers screened, 104 had MRSA either in the nose, hand or both giving a carriage rate of 52.5%. Nasal carriage (38.9%) was higher than hand (25.3%). Doctors (22.7%) and Nurses (16.7%) were the predominant carriers. MRSA isolates were resistant to commonly available antibiotics. Only 1 (1.3%) of the nasal isolates was vancomycin resistant. Conclusion: MRSA carriage among healthcare workers in the critical care units of the Nigerian hospital is high with doctors and nurses being the major carriers. The MRSA isolates were multi-drug resistant which may lead to increased morbidity and mortality if transmitted to the critically-ill. There is need for MRSA control policies in hospitals with settings of our type.
  Saidu Rakiya , B.O. Bolaji , Olatinwo Awo , McIntosh Cheri , Alio Amina and Salihu Hamisu
  To evaluate maternal characteristics that may be predictive of abnormal blood-loss among women undergoing repeat cesarean delivery. The retrospective case controlled study consisted of case notes of women with cesarean deliveries (December-January 2009). After exclusion of women without a prior cesarean delivery, only 104 were used for analysis. The researchers assessed the relationship of abnormal blood-loss and key characteristics that included: Age, parity, type of cesarean delivery, booking status, cadre of attending staff, abdominal scar, type of anesthesia, gestational age and length of hospital stay. Continuous data were analyzed using the student t-test and categorical data were analyzed using the χ2-test. The independent association between the exposures and outcome of interest was assessed with multivariable logistic regression. As compared to mothers with parity of less than four, mothers with a higher parity and abnormal blood loss were 8 times more likely to experience abnormal blood-loss (Adjusted OR = 8.1, 95% CI: 1.2-53.5). Diffrence in risk was also observed between length of hospital stay and blood-loss status. No difference in risk was observed between the any of the other maternal characteristics and abnormal blood-loss. Cesarean deliveries in developing settings carry a greater risk compared to those performed in developed locations, especially among women enduring a repeat cesarean delivery. The risk of abnormal blood-loss among women in the study with parity of greater than four was substantially high. There is need for additional research to understand the association between high parity and abnormal blood-loss in developing settings.
  F.O. Omosofe , B.O. Bolaji , I.K. Kolawole and A.B. Makanjuola
  The clinical efficacy of Electroconvulsive Therapy (ECT) depends on the induction of generalized cerebral seizure activity. One goal of anaesthesia for ECT is to relax the voluntary muscles with the aim of reducing convulsive activity and thereby minimize the risk of physical harm to the patient. An anaesthetic induction agent with rapid recovery profile will therefore be most suitable for modified ECT. The aim of the study was to compare the seizure duration and recovery profile of thiopentone and propofol following modified electroconvulsive therapy. In a prospective, randomized, double-blind study, sixty consecutive patients scheduled for ECT were randomly allocated into the unmodified, thiopentone and propofol groups with twenty in each group. Anaesthesia was induced with 1 mg kg-1 of Propofol (PG) and 5 mg kg-1 of Thiopentone (TG) and intravenous suxamethonium chloride was administered at a dose of 0.5 mg kg-1. Anaesthesia was not administered to the patients in the Unmodified Group (UG) which served as control. The patients’ heart rate, blood pressure and arterial oxygen saturation were monitored during the procedure. The duration of seizure and the time taken to gain full recovery in the groups were also compared. The shortest mean seizure duration was recorded in PG (23.30±3.06 sec) compared with 34.20±4.35 sec in UG and 28.25±3.58 sec in TG. The duration was significantly less in PG than TG (p = 0.008). The mean time to eye opening and obeying command was significantly less in PG than TG (p = 0.009 and 0.006, respectively) but time to full orientation was not significantly different (p = 0.080). Propofol produced a significant reduction in seizure duration but it is not better than thiopentone with regards to recovery characteristics after ECT.
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