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Articles by B.A. Ayinde
Total Records ( 2 ) for B.A. Ayinde
  M. Idu , F.E. Oronsaye , C.L. Igeleke , S.E. Omonigho , O.E. Omogbeme and B.A. Ayinde
  The phytochemistry and antimicrobial effects of water, methanol, chloroform and petroleum ether extracts of Senna alata leaves were studied. Extracts tested at a final concentration of 500 μg mL produced in vitro antimicrobial activities in assays against clinical isolates of Staphylococus aureus, Candida albicans, Escherichia coli, Proteus vulgaris, Pseudomonans aeruginosa and Bacillus subtilis. The zones of inhibitions produced by the extracts in agar diffusion assay against the test micro organisms ranged from 8 to 20 mm while the gentamycin antibiotic control produced zones that measured 5 mm. Preliminary phytochemical analysis of the plant extracts showed the presence of phenols, tannins, anthraquinoes, saponins, flavonoids.
  J.E. Ataman , D.B. Grillo , E.K.I. Omongbai , M. Idu , F. Amaechina , V. Okonji and B.A. Ayinde
  Phytochemistry of Momordica charantia L. leaves revealed the presence of flavonoids and tannins. The hypoglycaemic effect of M. charantia leaves as well as the plant`s effect on rats` weight under different treatment patterns was assessed. Forty wistar rats weighing between 140-250 g were categorized into eight experimental groups of five wistar rats per group. The efficacy of 250 mg kg-1 methanolic extract of the leaves on alloxan-induced diabetic rats showed mild hypoglycaemic effect within 24 h. There was no evidence to establish that parenteral route is more efficacious than the oral route of administration of the treatment plant. The experimental rats that was alloxan-treated to induce hyperglycaemia and treated with 500 mg kg-1 of methanolic extract of the treatment plant as well as those induced with alloxan without treatment with methanolic extract of M. charantia showed significant loss in weight (p < 0.05) after twelve weeks. The controls as well as those treated exclusively with methanolic extract of treatment plant without alloxan treatment had significant weight gain (p < 0.05). The results generally indicate that methanolic extract of the leaves of M. charantia has hypoglycaemic potential especially on long-term use.
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