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Articles by B. Nithya
Total Records ( 2 ) for B. Nithya
  P. Ponmurugan and B. Nithya
  Soil samples were collected from different states in Southern India to isolate and characterize actinomycetes at molecular levels through plasmid DNA and protein pattern. A total of 12 soil samples were collected from which four strains (AP-1, KN-2, KL-3 and TN-4) were isolated and characterized as Streptomyces sannanensis. The antimicrobial activity of these strains was studied against gram-negative and positive-bacteria. It was capable of producing antibiotic against gram-positive, while gram-negative bacteria were not affected. The potential of antibiotic production of these strains is likely to be chromosomally encoded by confirming the detection of plasmid DNA. The strains such as KN-2 and KL-3 showed two plasmids and the other two strains showed only one. This is a preliminary step to correlate the chemotaxonomic relationship among the strains of Streptomyces spp. for secondary metabolite production.
  B. Nithya and P. Ponmurugan
  A study was undertaken to isolate biologically diverse strains of actinomycetes from medicinal plants rhizosphere soil collected from different locations of Yercaud hills belonging to Eastern Ghats of southern India for the production of bioactive secondary metabolites. The results indicated that a total of 20 strains were obtained from soil samples and further correlated with soil nutrients status in which five novel strains were screened for further investigation based on in vitro performance. The bioactive antimicrobial compounds were extracted from the purified cultures and tested their efficacy against some human pathogenic microorganisms such as Staphylococcus aureus, Escherichia coli, Bacillus amyloliquefaciens, Serratia marcescens and Pseudomonas fluorescence and beneficial microorganisms such as Phosphobacteria (PSB), Potassium solubilizing bacteria (KSB), Azospirillum and Rhizobium spp. including tea plant pathogens namely Phomopsis theae and Tunstallia aculeate. The results showed that all the strains were found to be of potential antagonists against the tested pathogens and thus providing the production of secondary metabolites.
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