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Articles by B. Joseph
Total Records ( 8 ) for B. Joseph
  B. Joseph and S. Sujatha
  In the present study, we evaluated antimicrobial activity of clove oil against a range of food borne pathogens like bacteria and fungal autochthonous microorganisms and study the bioactive compounds present in the clove oil (dry) and its bioactivity. The Syzygium aromaticum Clove oil (extracted) and acetone based extracted clove oil analyzed by GC-MS. It contains a three higher peak as well as three lowest peak important phytochemical compounds such as Eugenol, a-cubebene, Iso-eugenitol and a-copaene, β-Caryophyllene oxide and β-Bipinene, respectively. The GC-MS analysis showed the presence of various secondary bioactive compounds and its antimicrobial activity of dried clove oil and crude extract against pathogenic bacteria like gram positive (seven) and three Gram negative (Escherichia coli, Salmonella sp. and Klepsiella pneumoneae). This results showed that the relative analysis of acetone extract (50%) of crude clove extract and clove oil as a natural autochthonous antimicrobial agent on some food spoilage gram negative as well as gram positive bacteria. The oil was found to be very effective with a lowest minimum inhibitory concentration (MIC) of 2.5% (v/v) against Staphylococcus epidermidis and Staphyl sp. amongst the fungi, Aspegillus niger and Rhizopus sp., was found to be highly sensitive to the oil. Sorbic acid (std food preservative) was used as a positive control. Clove oil was found to be more effective when compared to both clove extract and Sorbic acid. This study shows the potential of clove oil to be used as food bio-preservative.
  B. Joseph and S.J. Raj
  Phyllanthus amarus (Euphorbiaceae) is a widely distributed small erect, tropical annual herbal whose stem has green capsule and grows upto 10-60 cm tall. The plant is bitter, astringent, cooling, diuretic, stomachic, febrifuge and antiseptic. It is popular in indigenious system of medicine like ayurveda, siddha, unani and homoeopathy and is used for its hepatoprotective, antitumour, antidiabetic, antihypertensive, analgesic, anti-inflammatory and antimicrobial properties. The plant is also used in dropsy, jaundice, diarrhoea, dysentery, intermittent fevers, diseases of urino-genital system, scabies, ulcers, wounds and cold. Its has a good anti-viral activity against hepatitis B virus. It also has anti- nociceptive and anti- inflammatory activities, antidiabetic and antilipidemic potentials. The present review is therefore, an effort to give a detailed survey of the literature on its pharmacological, traditional and phytochemical properties.
  B.Y. Kamaruzzaman , A. Siti Waznah , M.S. Mohd Zahir , M.C. Ong , S. Shahbudin , K.C.A. Jalal , Z. Rina Sharlinda , A.T. Shuhada , B. Akbar John , B. Joseph , S.M. Al-Barwani and J.S. Goddard
  Bottom sediments from 62 stations at Pahang river-estuary were analyzed for the concentrations of Chromium (Cr), Manganese (Mn) and Cobalt (Co). Heavy metal concentrations were analyzed by using an Inductively Coupled Plasma Mass Spectrometry (ICP-MS). The average dry weight concentrations of Cr, Mn and Co were 62.80±20.04, 416.21±127.41 and 7.93±3.25 μg g-1, respectively. The observed concentrations of the studied metals were significantly higher near the estuary and declining as the sampling points were further away from the estuary. The Enrichment Factors (EFs) were calculated and all elements showed metal contamination was predominantly of terrigenous in origin.
  B.Y. Kamaruzzaman , M.C. Ong , S.Z. Rina and B. Joseph
  In this study, the concentration of Pb, Cu and Zn were determined in muscle, gills and stomach of six fish species caught from Pahang river estuary. These metals concentration were measured by ICP-MS in order to assess the fish contamination with these metals. This study showed that all catfishes (Arius sp.) presented the highest metals content. Tissue analysis revealed that the stomach accumulated the highest level of these metals. Based on the results, metal concentration in the edible part of the examined fish (muscle) were in the safety permissible levels for human consumption.
  G. Adiana , B. Joseph , N.A.M. Shazili , M. Mohamad and H. Juahir
  A research expedition was carried out off the Borneo Island coastal in order to define the current level and behavior of metals in the water column of Sulu and Celebes Seas. Water samples were collected at 37 stations off Sabah and Sarawak coasts. Samples were then pre-concentrated using Chelex-100 resin, preserved on-board ship prior transportation to the laboratory and finally, analyzed using Inductively Coupled Plasma Mass Spectrometry (ICP-MS). Overall, the vertical profiling of metals showed no distinctive patterns. In the meantime, the Principal Component Analysis (PCA) showed a group of bioactive metals and abundance metals in the upper continental crust. Additionally, PCA showed the decrease in of temperature and salinity led to increase of Dissolved Oxygen (DO) in depth. Besides that, the elements partitioning exhibits that Chromium (Cr), Nickel (Ni), iron (Fe) and lead (Pb) has the strongest adsorption onto Suspended Particulate Matter (SPM) whereas Cadmium (Cd), Zinc (Zn) and Aluminium (Al) showed the weakest bond with SPM. In brief, data collected throughout the present research has evidence the influenced of land-based contaminants into the water column as well as the physico-chemical characteristics of Sulu and Celebes Seas off Malaysian waters.
  S. Sujatha and B. Joseph
  Aim of the present study was planned to assess the biodiversity of the marine environment around the Muttom coastal region and then to isolate and characterized the secondary metabolites from the eleven sponges and screen them for their mosquito larvicidal effect. Due to increasing resistance of the vectors mosquitoes causing diseases of importance in public health, to chemical insecticides, is necessary the searching for alternative control methods, as the use of marine sponges extracts with insecticide activity, owing to its capacity of biodegradation and generation of minor environmental damage. In this work the insecticide activity is evaluated for the mixture of chloroform with methanol extracts of the eleven marine sponges on stadium V instar larvae of Aedes aegypti (L.) and Culex quinquefasciatus (L.) in conditions of laboratory (25°C and 75% Relative Humidity). The sponge extracts of Clathria gorgonoids and Callyspongia diffusa was found to be the most effective against A. aegypti larvae showed LC50 values at <50 ppm. A result demonstrates that Ircinia campana extract is most active against two insects, as long as the extract of Sigmadocia carnosa has a higher toxic effect on Aedes aegypti than on Culex quinquefasciatus. Between the sponges Clathria gorgonoids and Callyspongia diffusa were found to be more active towards both larvicidal and insecticidal properties. In view of both these activities, the subsequent sponges Haliclona pigmentifera, Sigmadocia carnosa, Petrosia similes and Ircinia fusca could be used to obtain novel pesticidal molecules.
  B. Joseph and R.M. Priya
  Essential oils distilled from aromatic and medicinal plants have been used both cosmetically and therapeutically. Nowadays, Psidium guajava L. plant parts are commonly used as medicinal plant. Although, there is considerable anecdotal information about the biological activity of guava essential oils much of this has not been substantiated by scientific evidence. Among the claims made for Psidium guajava (L.) essential oil is that have antimicrobial, antinociceptive, repellent, insecticidal, anticancer and anti-inflammatory effects. In this study we detail the current state of knowledge about the effect of guava essential oils and phytochemicals.
  B. Joseph , S. Sridhar , Sankarganesh , Justinraj and Biby T. Edwin
  The main objective of this review is to provide advance information for the drug discovery research from rare medicinal plant Kalanchoe pinnata, which has potential anticancer and insecticidal compounds etc. This plant leaf and stem and leaf portions contains significant chemicals which are most needed in medicinal industry, e.g., Bufadienolides. It is potential anticancer and insecticidal active compound. The other phytochemicals proved against UTI, parasitic, bacterial infections, antiulcer active and antidepressant. Now it becomes endangered plant which needs to be conserved as well as explored for its significant green chemistry.
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