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Articles by Azrina Azlan
Total Records ( 8 ) for Azrina Azlan
  M.H. Nurulhuda , Azrina Azlan , Amin Ismail , Zulkhairi Amom and Faridah Hanim Shakirin
  The present study was designed to explore the possible cholesterol lowering effect of Sibu Olive (SO) supplementation on cholesterol level and atherosclerosis inhibitory effect in hypercholesterolemic rabbits. A total of five groups (n = 7); NC (normal diet), PC (normal diet+0.5% cholesterol), HS (hypercholestrolemic diet+10 mg kg day-1 simvastatin), HF (hypercholsterolemic diet+5% fullfat SO) and HD group (hypercholesterolemic diet+5% defatted SO) were established. Body weight and lipid profile analysis [total cholesterol, low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C)] were compared to PC. There was rise in body weight changes (1.75-2.24 kg) of the animals. The HD group showed significant reduction in total cholesterol (96.3%) and LDL-C (26.5%) together with increment in HDL-C (46.8%) relative to PC. Furthermore, the atherosclerotic plaque formation in HD group diminished by 79.4% compared to PC. The possible cholesterol lowering effect was contributed by the presence of polyphenols such as phenolic acids, flavonoids, anthocyanidins and anthocyanin of the SO fruit. Hence, these findings are beneficial as it provide alternative means to treat hypercholesterolemia and atherosclerosis.
  Muhammad Rizal Razman , Azrina Azlan , Jamaluddin Md. Jahi , Kadir Arifin , Kadaruddin Aiyub , Azahan Awang and Z.M. Lukman
  Consumers take part in essential role in contributing to the development of the country’s economy which include urban region as the result there are many conferences, symposiums and seminars which have been organised for the purpose to enhance the awareness on their rights. Therefore, this study will discuss on how the Malaysian statutory implied terms in the sale of goods law provide protection to consumer protection on food and environmental safety focusing on urban sustainability. The core reference of this study is based on Malaysian Sale of Goods Act, 1957.
  Azrina Azlan , Yu Wei Kok and Hock Eng Khoo
  This study aimed to determine antioxidants content and antioxidant activity of Polyphenol-Rich Mixture (PRM) samples containing garlic, ginger, lemon, apple cider vinegar and honey. Three PRM samples (raw, cooked and commercial) were subjected to Folin-Ciocalteu reagent and aluminium chloride colorimetric assays for determination of Total Phenolic Content (TPC) and Total Flavonoid Content (TFC) respectively. Antioxidant activity was determined based on DPPH free radical scavenging and Ferric Reducing Antioxidant Power (FRAP) assays. TPC and TFC of the three samples were significantly different (p<0.05) where cooked and commercial PRM had the highest antioxidants content. Similarly, cooked and commercial PRM showed the lower EC values indicating both samples possess higher antioxidant activity compared to raw PRM. The 50 cooked and commercial PRM also had higher FRAP values which showing a significant difference between the PRM samples (p<0.05). Pearson correlation analysis demonstrated high negative correlations between DPPH scavenging activity and total phenolics (TPC and TFC) with r = -0.855, r = -0.829, respectively. FRAP values of the PRM samples were also positive and highly correlated with TPC and TFC (r = 0.995, r = 0.988, respectively). This finding clearly indicated that cooked and commercial PRM possess high antioxidants content and antioxidant activity and can be considered as potential natural antioxidant beverages for prevention of chronic diseases.
  Chai, Min Ying , Azrina Azlan , Sadeq Hasan Al-Sheraji , Fouad Abdulrahman Hassan and K. Nagendra Prasad
  This study was aimed to determine and compare Total Phenolic Content (TPC) and Antioxidant Activities (AA) in germinated and non-germinated legume [peanut (Arachis hypogeal) and soybean (Glycine max)] extracts prepared using alkaline-acid hydrolysis. Total phenolic content and antioxidant activities 1, 1-diphenyl-2-picrylhydrazyl free radical (DPPH) scavenging and reducing Ferric Ion Antioxidant Potential (FRAP) in extracts were determined spectrophotometrically. Total phenolic content in non-germinated peanut and soybean were 1090.58 and 888.08 mg GAE/100g dry weight, respectively. After germination, total phenolic content in peanut increased to reach 1151.33 mg GAE/100g dry weight; while soybean significantly decreased. In non-germinated peanut and soybean DPPH was 1084.99 and 507.59 μM TE/100g dry weight; and FRAP was 47966.67 and 23010.00 μM Fe2+ equivalent/100g dry weight respectively. Following germination, DPPH and FRAP were decreased in peanuts but increased in soybeans. The process of germination has resulted to the increments of antioxidant activities in soybean and total phenolic content in peanut.
  Hock Eng Khoo , See Meng Lim and Azrina Azlan
  This review covers potential health benefits and efficacies of anthocyanins as well as anthocyanidins, in the prevention of several diseases. Blue, red and purple coloured fruits, vegetables and grains are rich in anthocyanins and have several health benefits, such as prevention of chronic diseases, antimicrobial, antioxidative and anti-inflammatory effects as well as improve vision and memory. Various in vitro and in vivo studies demonstrated the efficacy of anthocyanins in fruits and vegetables for the prevention of diseases and other health benefits. Most of the studies showed positive results towards the improvement of disease conditions. In short, anthocyanins and the anthocyanin-rich extracts are some of the best remedies used in prevention of several diseases, memory enhancement and behavioural improvement.
  Muhammad Rizal Razman , Azrina Azlan , Jamaluddin Md Jahi , Kadir Arifin , Kadaruddin Aiyub , Zahan Awang and Z.M. Lukman
  Agenda 21 based on parts 19.1 and 19.11 highlighted that there are thousands of chemical substances in the world market, a lot of which emerge as poison and toxin in business goods, food and the variety of environmental medium especially in urban area. This has shown that chemical substances bestow awful impact to the environment which includes urban area. Therefore, this study will classify the relevant Malaysian laws on environmental management that managed chemical substances particularly in urban area in order to achieve urban sustainability. This study also has become aware of that there is no specific law in Malaysia that governed the environmental management on chemical substances. However, there are several laws that regulate the environmental management of chemical substances in different area such as the Environmental Quality Act 1974. The Environmental Quality Act, 1974 is related to the control of chemical substances in air and hazardous wastes whilst the Food Act, 1983 controlling chemical substances in the products and goods in the food industry. As for the Occupational Safety and Health Act, 1994 is on regards chemical substances in the occupational environment and meanwhile the Pesticides Act, 1974 to control chemical substances in pesticides. Meanwhile the management of these laws is not the responsible of a single government ministry. Different government ministries may enforce the laws relevant to the operation of that ministry. Hence, the Environmental Quality Act, 1974 is the responsible of the Ministry of Natural Resources and Environment, the Occupational Safety and Health Act, 1994 is by the Ministry of Human Resources whilst the Food Act, 1983 is by the Ministry of Health and as for the Pesticides Act, 1974 under the supervision and administration of the Ministry of Agriculture and Agro-based Industry. Finally this study has concluded that Malaysia has a sufficient laws in which may adequately control chemical substances in various life cycles as to comply with international law particularly in urban area in order to achieve urban sustainability.
  Muhammad Rizal Razman , Sakina Shaik Ahmad Yusoff , Shamsuddin Suhor , Azrina Azlan , Rahmah Ismail , Azimon Abdul Aziz and Kartini Aboo Talib Khalid
  Environmental sustainability is based on the concept of sustainable development. Environmental sustainability promotes the capacity to sustain the quality of life for consumer in order to safeguard environment as well as to protect consumer against harm, especially towards better living environment for consumer. One of the national laws of Malaysia that harmonised the concept of sustainable development in order to achieve environmental sustainability for consumer protection is the Sale of Goods Act, 1957. Therefore, this study will discuss on how the Malaysian Sale of Goods Act, 1957 provides protection to consumer protection and environmental sustainability on drinking bottled water which focusing on statutory implied terms.
  Nawal S. Hasan , Zulkhairi H. Amom , A.I. Nor , Daryl J. Arapoc and Azrina Azlan
  The influence of dates extract on lipid profile and atherosclerotic lesion formation in hypercholesterolemic induced rabbit were investigated. About 49 male New Zealand White (NZW) rabbits were divided into 7 groups. The Normal Control (NC) group, Hypercholesterolemic Control (HC) group was given 0.5% cholesterol diet, Simvastatin Control (SC) group was given 0.5% cholesterol diet+5 mg kg-1 simvastatin. Treatment groups T125, T250, T500 and T1000 were given 0.5% cholesterol diet with supplementation of 125, 250, 500 and 1000 mg kg-1 of dates extract, respectively for 10 weeks. Blood was collected from ear vein for plasma analysis and the whole aortas were excised for microscopy study. The supplementation of 125 and 250 mg kg-1 of date extract reduced plasma Total Cholesterol (TC), Low-Density Lipoprotein (LDL) and Triglycerides (TG) levels concomitantly groups supplemented with date extract (T125, T250, T500 and T1000) were significantly higher (p<0.05) in High Density Lipoprotein (HDL) in diet induced hypercholesterolemic rabbit. The Atherogenic Index (AI) and sdLDL values were found to be lower in date extract treated groups compared to HC (p<0.05). The plasma total antioxidant activity in groups, treated with date extract (T125, T250, T500 and T1000) were significantly higher (p<0.05) in compared to HC group at 10th week. No foam cell formation was visible in the aorta of rabbits in NC and T250 groups. However, there was visible foam cell formation in the aorta of groups HC, SC, T125, T500 and T1000. Results showed that plasma lipid concentration was significantly reduced at the end of experiment in groups supplemented with date extract.
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