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Articles by Ayhan ABACI
Total Records ( 2 ) for Ayhan ABACI
  Samil Hizli , Nur Arslan , Ayhan Abaci and Benal Buyukgebiz
  Aim: To evaluate whether subclinical hypothyroidism (SH) is associated with anthropometry and fatty infiltration of liver in obese adolescents.
Materials and methods:
The adolescents attended with the complaint of obesity aged 11 to 15 years included in the study. Patients were diagnosed as obese adolescents with fatty liver. Age-, gender-, and body weight-matched obese adolescents without fatty liver seen during the same period served as controls. Clinical characteristics, laboratory parameters, and frequency of subclinical hypothyroidism (SH) of both groups were compared.
The study population included 218 adolescents with obesity. Of 218, 30 (13.7%) had fatty liver at ultrasonography (group 1) and the remaining 188 obese adolescents did not have fatty liver and served as control (group 2). The mean ages of groups 1 and 2 were 12.7 ± 1.25 and 13 ± 1.39 years; the rate of female participants were 43.3% and 55.8%; and, weight:height ratios were 157.2 ± 24 and 151.3 ± 19.8 (P = 0.37, 0.24, and 0.54, respectively). The prevalence of SH in patients with fatty liver was 10% and was not significantly higher compared to the controls (6.4%, P = 0.55).
SH seems to be a secondary condition rather than a triggering factor for development of fatty liver in adolescent obese patients. There was no statistically significant relation between subclinical hypothyroidism and fatty liver.
  Ayhan ABACI , Ahmet Zulfikar AKELMA , Osman OZDEMIR , Samil HIZLI , Cem Hasan RAZI and Kadir Okhan AKIN
  Aim: To evaluate the total homocysteine (tHcy) level, a risk factor for atherosclerosis, atherothrombosis, and insulin resistance, for sex and pubertal state differences in obese children. Its relationship with metabolic and anthropometric parameters was also investigated. Materials and methods: The study involved obese children with a body mass index (BMI) above the 95th percentile who presented with the complaint of excessive weight gain, and healthy children with a BMI below the 85th percentile. Results: The study included 100 obese (mean age: 10.2 ± 2.7 years) and 71 healthy nonobese (mean age: 10.9 ± 2.6) children. A comparison of the data from the obese group and the control group revealed that the differences in BMI, BMI standard deviation score, tHcy, total cholesterol, triglyceride (TG), insulin, high-density lipoprotein (HDL), low-density lipoprotein (LDL), and homeostasis model assessment-insulin resistance (HOMA-IR) levels were statistically significant (P < 0.05). In the obese group, the tHcy level was statistically significantly correlated with age and BMI, TG, and HDL levels (P < 0.05), while it was not statistically significantly correlated with total cholesterol, LDL, fasting glucose, insulin, or HOMA-IR levels (P > 0.05). Conclusion: The results of this study showed that the tHcy level was higher in obese children than in healthy children. However, the tHcy level was not significantly correlated with insulin resistance in obese children. Obese children should be routinely screened for high tHcy levels due to the potential atherosclerosis risks, and patients with high tHcy levels should be treated.
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