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Articles by Asia Karim
Total Records ( 5 ) for Asia Karim
  Asia Karim
  Not Available.
  Muhammad Nouman Sohail , Fiaz Rasul , Asia Karim , Uzma Kanwal and Idress Hamad Attitalla
  Viruses are one of the main hazards for both humans and animals. They enter in the living body and redirect body’s metabolism to produce large copies of their genome and proteins. Diseases caused by these viruses are difficult to tackle with the help of currently available antiviral drugs. So the aim of this study was to explore the plants with reported antiviral activity, to get understanding for better control of these viruses. Herpes virus, Human Immunodeficiency Virus (HIV), influenza and hepatitis virus were at top among all studied viruses. Prominent modes of action against these viruses were inhibition of viral entry and its replication in host cell. Against RNA viruses plants mainly targeted their Reverse Transcriptase (RT) enzyme (like HIV) or protease (mostly found against hepatitis C virus). A range of active compounds have been identified which could be the potential antiviral agents for future drug development. Some plants like Allium sativum, Daucus maritimus, Helichrysum aureonitens, Pterocaulon sphacelatum and Quillaja saponaria emerged to have broad spectrum antiviral activity. Detail study of their phytochemicals and mode of action against these viruses could be help full for more effective control of hazardous viruses.
  Asia Karim , Muhammad Nouman Sohail , Saba Munir and Saba Sattar
  After twenty years Pakistan will be the fourth largest country with respect to the diabetic individuals. For a developing country like Pakistan availability of modren medical facilities to every person is not possible. In addition to economic constrains, reported side effects of these modern drugs encouroged us to search for an economical and safe alternative that can cure this disease. Herbal plants (cheaper availability and with less or no side effects) have emerged as a potential candidate. This review focuses the effectiveness of herbs and herbal drugs which are commonly used in Pakistan against diabetes. Different search engines were explored including Pubmed, Google and Asci database (up to 2nd June 2011) by using different keywords. Priority was given to research article and information given by authentic organizations and federations. Ninteen plants, which were used by local people as vegetable or herbal remedy, were analyzed for their antidiabetic potentials on the basis of previously published literature. Varying levels of antioxidant, antihyperlipidemic, Insulin stimulating, nephroprotective and hepatoprotective activities of these plants have been reported in various studies. Out of the ninteen herbs O. sanctum, Z. officinale, T. foenum-graecum and P. amarus were found to be the most effective against diabetes. In future adaptive use of these herbs in daily life as food may help to slow down the pace of disease development in Pakistan. There are plenty of herbs for which the medicinal value is still to be inquired so that they can replace and used as an alternate of synthetic drugs.
  Muhammad Nouman Sohail , Asia Karim , Muhammad Sarwar and Abobaker M. Alhasin
  Various diseases are common in Pakistani population and major reason for their prevalence is the lack of modern health facilities. Current review was aimed to find the potential medicinal uses of Allium cepa, which is a culinary herb. A number of studies have proven its potential use against human pathogenic organisms. Its extract and powder was found to have inhibitory activity against tumor cells. Moreover scientifically proven hypoglycemic, cardioprotective and hypolipidemic activities suggest its potential use in diabetes and cardiovascular diseases. It is also useful to reduce the risk of bone injuries especially in females. Onion is a rich source of flavonoids, polyphenols, organic sulfur, saponins and many other secondary metabolites, which are mainly responsible for its medicinal activities. Its organic sulfur compounds, which contribute for its different medicinal potentials are sensitive towards cooking; moreover this sensitivity is also variety dependant which means it’s more beneficial in its raw form. On the basis of reviewed literature it is concluded that it possesses significant beneficial health effects and its incorporation in daily food especially in raw form will provide protection against many diseases.
  Asia Karim and Uzma Kanwal
  Not Available
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