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Articles by Arpita Chatterjee
Total Records ( 5 ) for Arpita Chatterjee
  Arpita Chatterjee and Gopeswar Mukherjee
  Radiation oncology is a widely accepted subject in all over the world for the treatment of malignancy. To study the innate as well as humoral immune response before and after radiation therapy in patients and also to estimate the level of tissue damage in them the present study was performed. The extent of tissue damage was determined by measuring the C-reactive protein and immunologic defense was estimated by measuring complement C3 for innate resistance and immunoglobulin IgG for the humoral response. The complement C3, IgG and C-reactive protein levels of cancer patients were significantly higher than the normal level. More increase in serum C-reactive protein level in every patient after radiotherapy was observed. In majority of the cases decrease of C3 and IgG level was estimated after prolonged radiation treatment. This indicated that radiation therapy, despite being a successful treatment for cancer, causes massive tissue damage; and cellular as well as humoral immunity remains at a low level after radiotherapy. Age is a crucial factor to tolerate such prolonged therapy treatment. Prolonged application of radiotherapy may also cause side effects on normal immune system as they are already in immune deficient state due to the life threatening neoplastic disease.
  Arpita Chatterjee
  A total of 3747 cases were assessed to understand the prostrate cancer profile in the population of West Bengal from 2003-2010. Present investigation revealed that prostate cancer rate was climbing with 5.71% incidence and the ignorance is partially responsible for that alarmingly high incidence in elder males particularly from 51-70 years age group. The level of PSA (Prostate Specific Antigen) in the blood was high (<4 ng mL-1) in men having prostate cancer. The cancer frequency was moderate during 2003 to 2006, but it rises drastically from 2007 (17.76%) and reached maximum peak (28.97%) in 2010. Prostate cancer was most prevalent in group A, followed by group B and group O. The absolute number of new cancer cases was increasing rapidly, due to growth in size of the population and increase in the proportion of elderly persons as a result of improved life expectancy. The risk of developing prostate cancer was related to age, genetics, race, diet, lifestyle, medications and other factors. This peak cancer scenario can be altered in a positive direction by regular screening and by training the prevention measures of life style modification in a wide scale through proper way.
  Arpita Chatterjee
  Osteoporosis, characterized by low Bone Mineral Density (BMD) and micro-architectural deterioration of bone tissues is one of the major public health problem and is also increasing in developing world. Osteoporotic fracture entails high health care costs, frequently associated with loss of quality of life with an increased mortality risk. Physical activity has beneficial effects on the skeleton by contributing significantly to attainment of peak bone mass. In this cross-sectional study, a total of 26 volunteers (8 male and 18 female) were enrolled to understand of BMD profile, using Furuno Ultrasound Bone Densitometer CM 200, where dance movements is admitted as a form of physical activity. Controls (n = 25) were participants frequency matched to cases by age, sex, similar lifestyle and food habit except they do not practice dance movements. Results revealed that physical activity in regular manner showed higher bone strength. The BMD, as judged by T-scores were under normal value (-1.0) in cases but the value was lower (-1.2) in control group. Beside 16% of control participants showed presence of osteopenia and in 4% case osteoporosis. This result supports the fact that the physical exercise has a potential to increase the health status of any age group by eliciting positive changes in certain aspects of physical fitness and healthy wellbeing. The frequency of decreased value of BMD in controls with increasing age significantly constitutes a high-risk group for osteoporosis and future fractures.
  Arpita Chatterjee
  Oxidative stress injury induced lipid peroxidation and the impairment of the antioxidant system has a potential role in the pathogenesis of many diseases. Free radicals in form of oxidative damage causes fatal diseases and oxyradical-induced cytotoxicity arises from both chronic and acute increases in reactive oxygen species, which give rise to subsequent lipid peroxidation. Antioxidants act as free radical scavengers and hence prevent and repair damage done by the free radicals. The present investigation revealed that dance, as a form of physical activity, have a significant contribution to the healthy-living agenda. In comparison with non-dancers, due to prolonged practice of dance, the dancers also show high levels of antioxidants with low level of LPP. The decreased levels of antioxidant and increased levels of LPP indicate that due to lack of physical exercise the non-dancers may have chance of higher incidences of infections or immune complex diseases. In case of dancers, as a complete exercise, dance plays an important role in immunity as an early defence system against infections and has a potential role in oxidative stress induced lipid peroxidation and the impairment of the antioxidant system.
  Arpita Chatterjee
  The assessment of severity with chronological development of disease of mesta (Hibiscus cannabinus, cv. HC-583) on a particular diseased plant was studied. Based on the symptomatology and intensity of diseases caused by Begomovirus an empirical formula was developed. A methodology for assessing the disease intensity of yellow vein mosaic disease of mesta grown under natural field condition was proposed and it was validated by comparing with infected plants grown under field as well as glasshouse conditions. Quantitative assessment of the disease indicated that the disease index value at different stages of pathogenesis varied from 1.82 to 49.44 under field condition whereas the same varied from 2.78 to 50.83 under glasshouse condition. Mortality of infected leaves was noticed when the index value reached maximum. With the present methodology scoring of gradual development of disease has become possible for a particular plant and even for an individual leaf of a particular cultivar.
 
 
 
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