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| Articles
by
Arash Pezeshki |
Total Records (
2 ) for
Arash Pezeshki |
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Ali Rezaie
,
Arash Pezeshki
,
Behzad Zadfattah
,
Mehrdad Nazeri
,
Changiz Ahmadizadeh
and
Babak Mohammadi
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Celandine with scientific name Chelidounium majus, spreads across the world and exists in Northern parts of Iran like Gilaan, the outskirts of Rasht, Roodbar and Mazandaran. Some of effective chemical compounds are: malic, copticine, cityicacid, chelerythrine, berberine, succinic acid and sangainarine acid. The herb’s other medical properties are: calmative, narcotic, anti spasm, lowering blood pressure, antibilious, cathartic and wormroot in internal uses. Epispastics and flesh wound amneliorator in external uses. Other chemical compounds of the herb have alkaloids that some of which are toxic those alkaloids are Chelidtine hemochelidotine, cheleritrine, sangainarine and protopine. In the present study, 30 Wistar male rats of 200-230 g weight and about 3 months old were used for laboratory experiments. Animals were kept in standard condition, at 20-25°C, 70% humidity and light cycle of 12 h lighting and 12 h darkness. Standard plates were used in order to feeding by method of ad-libitum, i.e., 24 h feeding. It can be concluded, generally that based on different studies the extract of celandine may affect via effecting on benzodiazepine receivers connected to GABA receivers (considering its flavonoid content). Based on the obtained results by the present study it can be said that according to sedation process the extract dosage of 400 mg kg-1 BW among other dosages has had more meaningful results and has a better sedation, pre-anesthetic and anti-anxiety effects compared with diazepam (p<0.01). |
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Ali Rezaie
,
Arash Pezeshki
,
Behzad Zadfattah
,
Mehrdad Nazeri
,
Changiz Ahmadizadeh
and
Babak Mohammadi
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| |
Hempseed with scientific name Cannabis sativa, spreads across the world. Hempseed oil’s fatty acids compounds were obtained from different parts of Iran with different weather and were tested. The herb contains canabidole, canabinol and canabidiolic acid. The herb is used for preparing some sedation drugs which are used in neural stresses, anxiety, migraine, asthmatic coughs as well as local anesthesia in dentistry. Stuart points out that all parts of hempseed are used in China traditional medicine. Its seed is used as tonic, strengthening, laxative, diuretic, calmative, gastric anti parasite and narcotic. Masson and Teobold say that hempseed has a great value for tetanus treatment. Hempseed is a real calmative for stomachache and digestive disorders as well as beneficial for cancers, ulcers and rheumatic pains. In the present study, 30 Wistar male rats of 200-230 g weight and about 3 months old were used for laboratory experiments. Animals were kept in standard condition, at 20-25°C, 70% humidity and light cycle of 12 h lighting and 12 h darkness. Standard plates were used in order to feeding by method of ad libitum, i.e., 24 h feeding. Especial dishes were used for water. The rats were numbered in groups consisted of 5 animals and were placed in especial cages. |
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