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Articles by Anjeanette Roberts
Total Records ( 2 ) for Anjeanette Roberts
  Elaine W. Lamirande , Marta L. DeDiego , Anjeanette Roberts , Jadon P. Jackson , Enrique Alvarez , Tim Sheahan , Wun-Ju Shieh , Sherif R. Zaki , Ralph Baric , Luis Enjuanes and Kanta Subbarao
  The immunogenicity and protective efficacy of a live attenuated vaccine consisting of a recombinant severe acute respiratory syndrome (SARS) coronavirus lacking the E gene (rSARS-CoV-ΔE) were studied using hamsters. Hamsters immunized with rSARS-CoV-ΔE developed high serum-neutralizing antibody titers and were protected from replication of homologous (SARS-CoV Urbani) and heterologous (GD03) SARS-CoV in the upper and lower respiratory tract. rSARS-CoV-ΔE-immunized hamsters remained active following wild-type virus challenge, while mock-immunized hamsters displayed decreased activity. Despite being attenuated in replication in the respiratory tract, rSARS-CoV-ΔE is an immunogenic and efficacious vaccine in hamsters.
  Tracey Baas , Anjeanette Roberts , Thomas H. Teal , Leatrice Vogel , Jun Chen , Terrence M. Tumpey , Michael G. Katze and Kanta Subbarao
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