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Articles by Amirreza Ebadi
Total Records ( 3 ) for Amirreza Ebadi
  Ali Rezaie , Amirreza Ebadi , Mehrdad Nazeri , Samad Rezaie and Fatemeh Elmi
  Aloe vera is a perennial succulent belong to the Lily (Liliaceae) family. This plant has been known as the healing plant. Aloe vera has been used for traditional medical purposes in several cultures for millennia. It has been demonstrated that Aloe vera has growth promoting activities. The objective of this study was to determination of the effect of Aloe vera on healing of the experimental skin wounds on rats and its comparison with zinc oxide. Zinc oxide is being used worldwide as an absorbent and protective compound. Its pharmacological properties are wide and its non-toxic material allows it to be used as a routine skin care substance. In current study, 70 female wistar rats where included in 5 groups. Full thickness incisional wound with 23 mm diameter was made with surgical scissors and scalpel. The whole operation was taking place under general anesthesia and analgesia circumstances. After making surgical wounds, rats are treated as mentioned in the text. Rats are observed for 21 days for wound closure process and inflammatory conditions taking place in wound. Biopsy intervals are 0 (the day of surgery), 3, 7, 14 and 21th day after surgery. In these certain days rats were euthanized and biopsies of wound sites were obtained. Wounds areas are also, measured by Scion Image ™ Software daily. At last, all data were analyzed using SPSS Statistics Ver.17. As a result, Aloe vera at the dose of 10% has significant healing properties compared to Zinc oxide. These data were validating under confidence surface of 95% (p<0.01).
  Ali Rezaie , Behboud Jafari , Ghafour Mousavi , Mehrdad Nazeri , Amirreza Ebadi , Changiz Ahmadeh and Elmira Habibi
  In the present study, sedative and anti-anxiety drugs such as chemical drugs are used for the sedation and anti-anxiety but due to their side effects and economical issues, the significance of research on finding sedative and anti-anxiety drugs with less side effects and their ability to substitute these synthetic drugs and substituting newer sedation and anti-anxiety compounds is obvious. Origanum majorana is one of the plants that have the effect sedation and anti-anxiety. The aim of this research was to examine the effects of sedative, pre-anesthetic and anti-anxiety of Origanum majorana with diazepam in rats to different groups of male Wistar rats received herbal extract Origanum majorana with doses (100, 200, 400 mg kg-1, IP) and diazepam with dose of (1/2 mg kg-1, IP) and dimethyl sulfoxide with the equal volume. About 30 min after assessing the relift/sleep inducing effect (induced sleep duration by ketamine 40 mg kg-1, IP) anti-anxiety effects (using elevated plus maze). The results show meaningful increase in the period of the sleep that had been made with ketamine and also meaningful increase in the spend time at open arms in the patient group with the previous. The results show that the dose of extract Origanum majorana 200 mg kg-1 relieving effects of sedative, pre-anesthetic and anti-anxiety and before.
  Yousef Doustar , Younes Anzabi , Amirreza Ebadi and Behbood Jafari
  Influenza is a viral disease which has been known in 1901AD in 1955, a kind of influenza virus was known as a factor caused disease that later on called avian plague because of high rate mortality. In the present study, the sub-type H9N2 of avian influenza virus (obtained from Razi Serum Producing and Research Center) which was cloned two times in embryonic eggs was inoculated to the SPF (Valo, Lohman, Germany) at their 3rd week by nasal drops: At first, SPF chickens were divided to 2 groups of 10 subjects; a group as a treatment group and another one as a control group. Then treatment group was infected by H9N2 sub-type of influenza virus with dosage of 107.5 EID50. The control group obtained normal saline serum nasally equal to the inoculated viral solution volume. In histopathological studies of lung and pleura of treated chicks with H9N2 sub-type influenza virus, propagated pneumonia which accompanies hyperemia and severs hemorrhage was observed in to allele and pleurisy sacs. In microscopic view, there is sever hyperemia and hemorrhage in allelic sacs, edama infiltration of fibrin and inflammatory cells, especially heterophylus in pulmonary' tissue inter-space. In the present study, the apoptosis of primary bronchial cells was observable in some cases which demonstrate significant changes compared with control group. Probably, the expression of apoptosis induction channel which has been discussed in Brydon's studies is a suitable justification for these changes. So, it must be noted that there are various channels in occurrence of cell death following infection by influenza virus and knowing these channels needs extensive studies.
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