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Articles by Amir Abbas Farshid
Total Records ( 2 ) for Amir Abbas Farshid
  Farnood Shokouhi Sabet Jalali , Amir Abbas Farshid , Siamak Saifzadeh and Sara Javanmardi
  The aim of this study was to examine the effectiveness of intra-peritoneal administration of honey in prevention or reduction of post-surgical peritoneal adhesions in dog. The study was conducted with 18 adult, female, mixed breed dogs with mean weight of 20±4.25 kg. A standardized surgical trauma (serosal trauma model) was made in the dogs’ descending colon to induce adhesion formation. Control group (n = 9) received saline treatment and in experiment group (n = 9) the lesions were covered with honey. Three weeks after laparotomy, the dogs were sacrificed and the adhesions were graded according to their degree of severity based on Evans scoring system. Overall, 66.66% (n = 6) of the control animals and 22.22% (n = 2) of the experiment animals presented with moderate (grade 2) and severe (grade 3) adhesions. In the control group, there were 3 (33.33%) dogs with grade-0 or grade-1 adhesions but in the experiment group there were 7 (77.77%) dogs with the same grades of adhesions. The difference between two groups was shown to be significant (p<0.05). Based on the results of this study, it was concluded that honey appears to be a useful covering for damaged peritoneal surfaces and had high effectiveness in reducing post-operative adhesions.
  Shabnam Jalili , Amir Abbas Farshid , Reza Heydari , Minoo Ilkhanipour and Shahpar Salehi
  The protective effects of vitamin E was investigated on the cardiotoxicity induced by endosulfan administration. Male rats in different groups were given endosulfan (2 mg per kg body weight per day in corn oil through gavage), vitamin E (200 mg per kg body weight twice a week in corn oil through gavage) and endosulfan and vitamin E at the same dose and route, to the control group corn oil is given at the dose rate of 2 mL per rat per day through gavage, for a period of 28 days. The animals were sacrificed and heart tissues were collected and subjected to histopathology. The result indicated, sever congestion, haemorrhages with interstitial oedema. In some places there was diapedesis of leukocytes. Myocardium showed different degrees of degeneration, some of the myofibrils were found to be granular with pyknotic nuclei. Thickening of wall of arteries were seen. In the Vitamin E and endosulfan treated group the above mentioned lesions were significantly decreased in their severity. This study brought to light the protective effects of vitamin E on the toxic pathological lesions caused by endosulfan administration.
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