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Articles by Ali Karami
Total Records ( 3 ) for Ali Karami
  Ali Karami , Peter Hindeersson , Niels Hoiby , Saeid Morovvati and Akbar Khalilpour
  Seven strains of the lyme disease agent, Borrelia burgdorferi isolated from skin and cerebrospinal fluid of patients with erythema migraines and acrodermatitis chronica atrophicans were examined for presence of linear and circular plasmids. By using two dimensional gel electrophoreses several linear and circular plasmid were identified, each strains contains 5 to 11 plasmid mostly linear, varying in size between 3 to 60 kb pairs, none of the strains has similar plasmid profile. Comparing plasmid profile of Danish isolates with plasmid profile of B. borgdurferi from different geographical area revealed similarity to Swedish isolates. After 42 passage of DK1 strain in BSK-II medium it has lost one 5.5 kb linear plasmid. PCR amplification of total plasmid from seven DK strains with primers designed from conserved region of OspA gene produced fragment with 822 bp similar to size of the primers span in published sequence. Cloning and sequencing of OspA gene from DK1 and DK6 strains has shown similarity between 75 to 95% to different B. burgdorferi. Electron Microscopy analysis of 25 kb plasmid revealed that this plasmid indeed has linear structure. DNA sequence of some fragments of 25 kb linear plasmid has shown similar sequence to eukaryotic viruses specially Vaccinia and Varriola.
  Ali Karami , Ali Malak , Pooya Vatankhah and Zeinabsadat Fattahi Saravi
  Although difficult endotracheal intubation is associated with increased morbidity and mortality, no consensus exists on the risk factors associated with this complication. Therefore, the aim of our study was to determine the prevalence and risk factors of difficult intubation in a large group of obese patients who had undergonelaparascopicsleeve gastrectomy. We retrospectively evaluated the records of 402 obese patients with body mass index > 35 m2 who had undergone the procedure. The variables of age, sex, thyromental distance (cm), jaw motion, history of sleep apnea, previous history of difficult intubation, difficult intubation during the bariatric surgery and modified Mallampathi grade were analyzed in each patient. The Mallampati grade 3and 4 and history of previous difficult intubation were the only statistically significant variables associated with difficult intubation. Based on the results of our study, these risk factors should be highly considered in the perioperative evaluations of the obese patients.
  Ali Karami , Saeed Reza Soltani , Pooya Vatankhah , Seyd Hedayatallah Akhlagh , Mansoor Masjedi and Masih Shafa
  Perioperative renal failure is one of the major complications following coronary artery surgeries, leading to increased morbidity and mortality rates in patients; necessitating renal replacement therapy and longer hospital and ICU stay. Considering the antioxidative effects of N-Acetyl Cysteine (NAC) and vitamin C in decreasing inflammatory factors, this study was designed to evaluate and compare the protective effects of these two agents on renal function of high-risk patients undergoing coronary artery surgeries. This study was a randomized clinical trial research. Ninety patients undergoing cardiac bypass surgery, who were considered as high-risk for postoperative renal failure, were randomized into 3 groups. Group A received NAC, group B received NAC plus vitamin C and group C received Dextrose water 5% as placebo. The agents were administered during and 12 and 24 h after the operation. Serum creatinine levels one day before the operation and also on 1st, 2nd and 3rd days after the operation were recorded and compared. The results revealed no significant differences in serum creatinine levels between the three groups in any of the evaluated days. Based on the results of our study, administration of NAC or its combination with vitamin C does not affect the outcome of renal function in high-risk patients undergoing cardiac bypass surgery.
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