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Articles by Aisha Javaid
Total Records ( 2 ) for Aisha Javaid
  Ruqaiya Hasan , Aisha Javaid and Tayyaba Abbasi
  The study was conducted to find out the effects of atenolol on blood lipid profile of common rabbits (Oryctolagus cuniculus). The administration of an oral dose of 0.6 mg atenolol kg-1 day-1 for 27 days produced a strong dyslipidemia, which was evident by a significant (p<0.05) reduction in mean plasma cholesterol and triglycerides levels, a marked alteration in mean HDL-cholesterol concentration and a non-significant elevated level of LDL-cholesterol. These findings suggest that atenolol is an inappropriate antihypertensive monotherapic agent for patients suffering with the abnormalities of lipid metabolism.
  Ruqaiya Hasan , Aisha Javaid , Habib Fatima and Wajeeha Safdar
  This study is done to find out the effects of atenolol on plasma electrolytes sodium, potassium, calcium and on serum enzymes, aspartate aminotransferase (AST) and alanine aminotransferase (ALT) of common rabbits Oryctolagus cuniculus following the administration of an oral daily dose of 0.6 mg atenolol for 27 days. Observations showed a non-significant rise in sodium concentration, a significant elevation and ultimate fall of potassium concentration and reduction of calcium levels significantly to half of the normal values. These findings suggest the diuretic action of drug; possibly the prolonged use cause the renal dysfunction. Long-term treatment of hypertension by atenolol may impair the hepatic function indicated by significant very low and high levels of serum AST and ALT, respectively.
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