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Articles by Ahmed Abduljabbar Jaloob Aljanaby
Total Records ( 3 ) for Ahmed Abduljabbar Jaloob Aljanaby
  Ahmed Abduljabbar Jaloob Aljanaby and Qassim Mmuhsin Hashim Alfaham
  Objective: The aim of this study was to detect 10 virulence genes in 50 Escherichia coli strains isolated from patients with different infections. Methodology: Different phenotypic assays and multiplex PCR were used to detect virulence genes. Antimicrobial susceptibility testing was performed to 14 antimicrobials types by disk diffusion method. Results: The most common virulence gene was feoB (98%) and at lower prevalence were genes eaeA and stx1 (4%). Escherichia coli strains were highly resistant to most antimicrobials. Conclusion: Escherichia coli strains isolated from patients with bacteremia were highly virulence and more resistance to antimicrobials than those isolated from other sites.
  Ahmed Abduljabbar Jaloob Aljanaby
  Background and Objective: Pseudomonas aeruginosa (P. aeruginosa) is considered one of the most dangerous opportunistic bacteria worldwide, live in hospitals and other environments such as sewage water and soil and cause different infections include pneumonia. The main aim of this study was to investigate antibiotics susceptibility pattern and genotypic detection of virulence genes in P. aeruginosa isolates from clinical and environment sources. Materials and Methods: A total of 120 P. aeruginosa isolates were collected from two sources, 60 isolates from sputum of patients with pneumonia and 60 isolates from sewage water. Antibiotics susceptibility testing was done according to Kirby-Bauer method. Polymerase chain reaction technique was performed to detect the prevalence of six virulence-associated genes. Results: All 120 isolates (100%) were resistance to amoxicillin. While, imipenem was the best efficient antibiotic against clinical and sewage water isolates. Fifty five clinical isolates (91.6%) and 41 sewage water isolates (68.3%) were multi-drug resistance (MDR). The Pap A, Fim H, feoB, iutA, hly and kpsMTII genes prevalence in clinical isolates with percentages 91.6, 100, 80, 95, 20 and 100%, respectively, while the same genes prevalence in sewage water isolates with percentages, 51.6, 68.3, 41.6, 35, 3.3, 5 and 41.6%, respectively. Conclusion: This study suggested that there was positive correlation between the high prevalence of virulence-associated genes and increase of antibiotics resistance in P. aeruginosa isolates.
  Ahmed Abduljabbar Jaloob Aljanaby and Haneen Mohammed Reda Jaber Alhasnawi
  Background and Objective: Burns infections and urinary tract infections are the most important prevalent diseases in Asian countries, such as Iraq. Klebsiella pneumoniae is one of the most important bacteria cause this type of infections especially in hospitals. Therefore, the aim of this study was to investigate the prevalence of multi-drug resistance K. pneumoniae and extended-spectrum beta-lactamases producing K. pneumoniae isolates from inpatients with urinary tract infection and burns infections in Al-Kufa hospital in Al-Najaf province, Iraq. Materials and Methods: A total of 285 clinical samples were collected from in-patients infected with urinary tract infection (141 urine samples) and burns infections (144 burns swabs). Fourteen different antibiotics were used by disc diffusion method and 13 antimicrobials resistance genes were used by PCR technique. Results: A total of 43 K. pneumoniae strains were isolated. The highest resistance rate was observed for amoxicillin 25 μg and amoxicillin+clavulanic acid 20+10 μg (97.67%) while the lowest resistance rate was observed for imipenem 10 μg (9.30%). The most common resistance associated-genes were blaSHV (86.04%) and at lower prevalence were IMP (9.30%). Conclusion: Klebsiella pneumoniae strains isolated from burns infections were more virulent than those isolated from urinary tract infections.
 
 
 
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