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Articles by Ahmad R. Gohari
Total Records ( 2 ) for Ahmad R. Gohari
  Ahmad R. Gohari , Soodabeh Saeidnia , Mahmood R. Gohari , Fahimeh Moradi-Afrapoli , Maryam Malmir and Abbass Hadjiakhoondi
  From the ethyl acetate and methanol extract of the aerial parts of Satureja atropatana Bonge, which belongs to the Lamiaceae family, four flavonoids were isolated. Their structures were determined to be 5,6,3’-trihydroxy-7,8,4’-trimethoxyflavone (1), 5,6-dihydroxy-7,8,3’,4’-tetramethoxyflavone or 5-desmethoxynobiletin (2), 5,6,4’-trihydroxy-7,8,3’-trimethoxyflavone or thymonin (3) and luteolin (4) using 1H and 13C-NMR and MS spectra. Brine shrimp cytotoxicity effects of the crude extracts and isolated compounds were examined. Berberine hydrochloride (LC50 = 26 g mL-1) was used as a positive control. Among them, compounds 2 (199 g mL-1) and 3 (157 g mL-1) were effective against Artemia salina larva.
  Ahmad R. Gohari , Soodabeh Saeidnia , Maryam Malmir , Abbass Hadjiakhoondi and Yousef Ajani
  The genus Salvia (Lamiaceae) contains more than 50 shrub species in Iran, and Salvia limbata C.A. Meyer grows widely in the north and central parts of the country. Six flavones and rosmarinic acid were isolated from the ethyl acetate and methanol extracts of the flowered aerial parts of S. limbata collected from Semnan province. The separation process was carried out using several chromatographic methods. Structural elucidation was based on NMR data, in comparison with those reported in the literature. The isolated compounds were identified as ladanein (1), salvigenin (2), luteolin 7-methyl ether (3), cirsiliol (4), eupatorin (5), luteolin 7-O-glucoside (6) and rosmarinic acid (7). Some of these flavonoids have been reported to show antibacterial and cytotoxic activities.
 
 
 
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