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Articles by Abiodun H. Adebayo
Total Records ( 2 ) for Abiodun H. Adebayo
  Omolola E. Omotosho , Rebecca Garuba , Femi Ayoade , Abiodun H. Adebayo , Oluwatosin E. Adedipe and Shalom N. Chinedu
  Musa x paradisiaca (plantain) isamong the major tropical staple foods. This study was designed to determine the proximate, mineral and fat soluble vitamins constituents of unripe plantain fried with three different oils (canola oil, soya oil and vegetable oil) and unripe plantain oven dried sample was used as the control. The vitamins were determined using High Performance Liquid Chromatography (HPLC). The result of the proximate analysis showed that the dried samples had higher levels of protein (25.2%), carbohydrate (50.1%), moisture content (13.3%), ash content (2.02%), crude fibre (7.73%) but low level of crude fat in comparison with the fried samples. Plantain fried with vegetable oil had the lowest levels of protein (20.84%), carbohydrate (26.93%), moisture content (13.1%), ash content (1.72%) and crude fibre (6.57%) but the highest level of crude fat (30.84%). Plantain fried with vegetable oil had the highest level of calcium (211.80±0.1 mg g–1) while the dried plantain samples had high level of sodium (233.80±0.07 mg g–1). Lead (Pb) was absent in the dried plantain samples. Dried plantain samples gave a higher value of vitamins A (0.08±0.01 mg g–1), D (0.02±0.01 mg g–1), E (0.01±0.00 mg g–1), K (0.05±0.00 mg g–1) compared to plantain sample fried with canola oil which gave low level of vitamin D (0.03±0.00 mg g–1), E (0.25±0.00 mg g–1) and K (0.03±0.00 mg g–1). However, there was a very high level in vitamin A (0.72±0.02 mg g–1). The result showed that drying in oven retains the nutritional contents of plantain compared to deep-fat frying. Canola oil is recommended for frying although soya oil is also good.
  Jacob O. Popoola , Abiodun H. Adebayo , Olugbenga S. Taiwo , Olayemi O. Ayepola and Ehi F. Okosodo
  Multi-Purpose Medicinal Plants (MMPs) are gaining unprecedented attention apparently because of their potency to contribute to the prevention and treatment of myriads of diseases. As such the toxicity of many herbs including the MMPs has always been a concern particularly relating to internal organs. The present study investigates the local knowledge use and in vitro cytotoxicity against two cancer cell lines; BGC-823 and HeLa cells on three (MMPs); Moringa oleifera (Lam) (Moringaceae) Andrographis paniculata (Burm. f) and Asystasia vogeliana (Benth) (Acanthaceae). The local knowledge was collated through Participatory Rural Appraisal (PRA) approach from selected locations in the Oke-Ogun area of Oyo state, Nigeria. Ethanolic extracts were used for the in vitro cytotoxicity study. The extracts were screened in two cancer cell lines (BGC-823 and HeLa cells) using the Sulpho Rhodamine B (SRB) assay. For the treatment of diseases, the local knowledge shows that A. paniculata recorded higher fidelity level on the treatment of malaria (95%), diabetes (80%), high blood pressure (87.5%), cancer and tumor (65.7%). The infusion of A. vogeliana in combination with the leaves of Cassia alata, Cymbopogon citrutus and fruit juice of Citrus aurantifolia recorded higher fidelity level in the treatment of malaria and chronic fever (74.8%), gonorrhea (65%) and leprosy (40%) suggesting better alternative to M. oleifera and A. paniculata. The medicinal relevance of the species in the treatment of diseases such as malaria, fever, high blood pressure, cancer, diabetes among others in local herbal medicine were revealed. Cytotoxicity assay on the two cell lines, BGC-823 and HeLa cells revealed that only the ethanolic extract of A. paniculata exhibited some level (moderate) of cytotoxic activity with IC50 values of 24.7 50 and 23.1 μg/mL, respectively. M. oleifera and A. vogeliana did not show any significant activity on the cell lines. The study highlights the importance of local knowledge in finding cost effective, potent and safe herbs for people and screening of the plant species for their activities against cancer cell lines.
 
 
 
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