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Articles by Abdolvahab Moradi
Total Records ( 14 ) for Abdolvahab Moradi
  Sima Beshart , Khodaberdi Kalavi , Abdolvahab Moradi , Hamid Reza Bazerafshan and Durdi Qujeq
  Several reports revealed that plasma level of essential trace elements like magnesium, calcium and phosphorus altered in diabetics. These micronutrients especially magnesium are suspected to have effective roles in pathogenesis and progression of diabetes. The studied subjects consisted of 96 diabetic volunteers (66.8%) females (mean age rate of 51.8±9.37) and (31.3%) males (mean age rate of 49.8±14.84) admitted in diabetes clinics of Gorgan city (Northeast of Iran). In these patients, the plasma level of Mg measured by simple sampling method due to a cross-sectional designated project. Glycated hemoglobin (HbA1c) also measured as a glycaemia control index. Hypomagnesia states were positive in 48 cases (50%). Housekeepers together with low educated individuals had significantly lower Mg plasma level as compared to other studied groups (p<0.05). No significant relationships were seen considering other variables. In respect to significant alterations of Mg plasma level that also reported in other such studies, it is recommendable to provide complementary supplication of such micronutrients for diabetics.
  Abdolvahab Moradi and Talat Mokhtari-Azad
  The aim of this study were to assess the presence of HPV esophageal infection among Iranian Turkmen who live in an area located in the cancer belt in Asia. The specimens derived from 120 patients previously diagnosed for Squamous Cell Carcinoma (SCC) non-cancerous tissue derived from esophagus. All specimens were examined for the presence of HPV DNA. PCR was utilized to amplify a 150 bp segment of HPV L1 gene using the consensus primers. The amplified region was subsequently sequenced to identify the HPV genotypes. The HPV DNA was detected in 49.4% of patients with SCC, and 58% of non-cancerous tissue of esophagus. The positive samples included HPV-16 (46.6%), HPV-6 (24.6%), HPV-66 (8.2%), HPV-52 (4.1%), HPV-18 (2.7%); 14% of cases were positive for more than one type of HPV. The results confirm the presence of HPV in both esophageal cancerous and non-cancerous tissues.These results imply two different interpretations: 1) Due to non-significant difference between the rate of HPV positive in cancerous and non-cancerous tissues, HPV has no important role in esophageal cancers, which is less probable. 2). Because of a highly incidence of esophageal cancer in Turkmen-Sahra region, the HPV is a possible etiologic agent in esophageal carcinogenesis, most probably acting synergistically with physical, chemical, and/or nutritional factors that have previously been found to be related to this malignancy in Turkmen-Sahra.
  Talat Mokhtari-Azad , Abdolvahab Moradi , Abbas Khodayari-Nemin , Mohammad Reza Keikhaee , Sudabeh Sargolzaei and Mahmud Shahrokhi
  Human Papillomavirus (HPV) infection has been shown as a risk factor in oral carcinogenesis. The association between HPV and benign and malignant neoplasm of oral mucosa, especially surface epithelium–derived tumors, is well established. The role of HPV in pathogenesis of odontogenic cysts and tumors has been published in few articles. The aim of this study was detection of HPV in Iranian patients with intrabony ameloblastoma and investigation of specific risk factors associated with ameloblastoma. One hundred intrabony ameloblastoma and 50 age–sex matched samples as controls were evaluated by polymerase chain reaction for the detection and typing of HPV. Fisher exact and chi square tests were used to assess the data. HPV DNA was detected in 32% of patients and 10% of controls. HPV–6 was the most prevalent genotype (31.6%) in infected cases. It was followed by HPV–11 (12.5%), HPV–16 (12.5%) and HPV–31 (3.1%). We found a significant association between presence of HPV and location of tumor (p = 0.02), traumatic history (p = 0.03) and ododontic therapy (p = 0.01). These findings indicated that HPV–6 probably is one of the most important etiologic agents in causing intraosseous ameloblastoma in Iranian population.
  Azad Reza Mansourian , Akhtar Saifi , Abdoljalal Marjani , Ezzetollah Ghaemi , Abdolvahab Moradi and Mohammad Ali Vakili
  The concept behind this study is to find out the prevalence and reasons for acute poisoning in the emergency unit of 5th Azar hospital in Gorgan which is the main department in the town. This study was a cross-sectional descriptive study, the sample population were all the patients with acute poisoning either intentionally or accidentally whom admitted to the emergency unit of the hospital during period of one year. This research was implemented using a questionnaires which was filled either by the patients themselves or by those accompany them. The collected data were analyzed using the proper statistical tests. We conclude that the pre-university students are the main age group, drugs and pesticides are major types for either accidental or acute deliberate self-poising.
  Saeedeh Eris , Ezzat Ollah Ghaemi , Abdolvahab Moradi , Azad Reaza Mansourian , Mohammad Reza Rabiei , Sepideh Bakhashande Nosrat , Ali Amirchaghmaghi and Ali Reza Ahmadi
  The aim of this study was to determine the prevalence and probable predisposing factors of Aphthous ulcer among the medical students. This project was a cross-sectional and descriptive study, which was carried out on 485 students of Golestan University of medical sciences in the north of Iran. Data was collected by filling the questionnaire. The gathered informations entered into SPSS software and were analyzed by Chi square method. The mean age of the students was 21.8 years. 36.9% (179 persons) of subjects had positive history and 8.9% (43 persons) of them had present Aphthous ulcer at the time of interview. 70.6% of students with positive personal history of Aphthous ulcer had positive family history of Aphthous ulcer too. Internal labial mucosa was the commonest site of the lesion among the subjects with present Aphthous ulcer. We found that gender, positive family history, the field of study, the form of diet and stress had a major correlation with the incidence of Aphthous ulcer.
  Abdollah Abbasi , Abdolvahab Moradi and Mohammad Javad Kabir
  As the Golestan province has been known as a high prevalent region for TB in Iran; present study was conducted to evaluate TB status in the province. Samples of sputum were obtained from 1205 pulmonary patients. All isolates initially confirmed by ziehl-neelsen`s staining. The collected data were analyzed by SPSS analytical software. A total of 1205 cases of pulmonary TB patients were identified during the study period. 642(53%) were males and 563(47%) females. Eighty present (80%) of cases had fever. Sputum had been shown to be in 79.6% of cases that in 20% of them it was bloody. Ninety-three present (93%) of cases had a history of coughing for more than 3 weeks. Twenty-five present (25%) had a history of TB in their families. BCG vaccination related scar was seen in forty-five present (45%) of cases. Tuberculosis has a higher incidence rate in the area and is more common in females than in males. Reoccurrence (recurrence) of TB seems to be higher in females than males. So it is essential to health care deputies to consider this group (females) as a high-risk group and to consider each contracted family; because of high family history of TB as a major risk factor. In addition to low occurrence of scar lesion following BCG vaccination, it is also needed to conduct better popular trends on vaccination strategies.
  Abdoljalal Marjani , Abdolvahab Moradi and Mohsen Saeedi
  The aim of this study was to determine the changes of plasma lipid peroxidation, zinc and erythrocyte Cu-Zn superoxide dismutase activity in patients with type 2 diabetes mellitus and healthy control in Gorgan city. Fifty type 2 patients with diabetes mellitus and 50 people without diabetes were included in this randomized study. None of patients studied had any diabetic complications. The levels of plasma malondialdehyde and zinc from type 2 diabetes mellitus patients (6.24±0.85 nmol mL-1 and 116.78±5.51 μg dL-1) and control groups (3.63±0.97 nmol mL-1 and 146.86±9.06 μg dL-1) were determined. Erythrocyte Cu-Zn superoxide dismutase activity from patients with diabetes (675.34±60.89 U g-1 Hb) and control groups (1052.70± 52.76 U g-1 Hb) were determined. The increased plasma lipid peroxidation and decreased plasma zinc and erythrocyte Cu-Zn superoxide dismutase activity that we observed in patients with type 2 diabetes mellitus may predispose to the development of cardiovascular complications. We propose that diabetic patients may have elevated requirement for antioxidants. Supplementation with zinc and vitamin or dietary free radical scavengers such as vitamins E and C or tomato, orange and etc. have a potential role in boosting antioxidant-related defences and maybe important in patients with diabetes.
  Iraj Shahramian , Abdolvahab Moradi , Lila Roosta , Malek Rakhshani , Abbas-Ali Moein , Saeed Shakeri and Azad-Reza Mansorian
  At the present time heroine dependency is treated by methadone. In order to determine the effectiveness of another medicine named buprenorphine, an interventional study has been carried out. In this interventional study of 70 patients, compared buprenorphine (2 mg) and low dose (20 mg) methadone as treatment for heroine dependence. Buprenorphine and methadone were administered daily for 15 days. There were 35 patients in each group. Comparison between groups for withdrawal sign and symptoms showed no significant differences. As compared with low-dose methadone and buprenorphine, it was shown that buprenorphine is a suitable treatment for heroine addiction in terms of decreased withdrawal sign and symptoms.
  Abdoljalal Marjani , Abdolvahab Moradi and Gholamreza Veghari
  The objectives of this study were to evaluate the effect of haemodialysis on plasma Cardiac Troponin I and cardiac enzymes before and after the dialysis process. Twenty two patients with Chronic Renal Failure (CRF) disease who were haemodialyzed at 5th Azar hospital of Gorgan Dialysis Center were recruited for this study (2005). The patients do not have coronary heart disease. Plasma cardiac enzymes showed no significant difference in the post dialysis group when compared with predialysis. Plasma levels of Cardiac Troponin I in 12 haemodialyzed patients were significantly increased in the postdialysis group when compared with predialysis, whereas plasma level of Cardiac Troponin I in 10 haemodialyzed patients were undetectable ( less than 0.1 μg L-1). The observation of meaningful increasing level of plasma Cardiac Troponin I in the haemodialyzed patients after the process of dialysis shows that Cardiac Troponin I is highly specific marker for Acute Myocardial Infarction (AMI) when compared with other cardiac enzymes and is particularly useful for detecting AMI in chronic renal failure and haemodialysis patients which can prevent sudden cardiovascular abnormality and sudden silent myocardial infarction in these patients.
  Ezzat Ollah Ghaemi Ghaemi , Didar Khorshidi , Abdolvahab Moradi , Akhter Seifi , Masomeh Mazendrani , Masod Bazouri and Azad Reza Mansourian
  Daily increasing of Staphylococcus aureus resistance to various antibiotics in particular penicillin and Methecilin has led the scientist to look fore new medicines in this area. In an in vitro laboratory studies, it has been demonstrated that ethanolic extract of Lemon verbena can prevent the growth of Staphylococcus aureus. In this study the efficacy of ethanolic extract of Lemon verbena against Staphylococcus aureus skin infection were assessed in an in vivo, in animal model. 200 λ of Staphylococcus aureus suspension, were inoculated intradermally on the shoulder of 63 laboratory 20-30 g mice. the mice were divided in to 4 groups, 2 control groups: Negative (without treatment) and positive(treated with Mupirucin) and 2 test groups that treated for 7 days by ointment prepared from ethanolic extract of Lemon verbena (group3), or injection of Lemon verbena solution (group 4). The status of wounds, the rate of recovery was studied and the presence of local pus after dissection of mice on day 8 recorded and compared with each other. The wound appearance in the second day, on the injection site of S. aureus, in Group 1, 4, 3 and 2 were 84.2, 66.7, 46.2 and 23.1%, respectively. In the final day, the lesion still was remained in 78.9, 23.1, 92.3 and 77.7% in groups 1 -4, respectively. The necrotic and wide wounds were more observed in groups 1 and 3 vs two other groups. The results from this investigation indicate that the ointment prepared from ethanolic extract of Lemon verbena is a proper medication to prevent the skin infection by Staphylococcus aureus in early phase.
  Shahryar Semnani , Gholamreza Roshandel , Nafiseh Abdolahi , Sima Besharat , Abbas-Ali Keshtkar , Hamidreza Joshaqani , Abdolvahab Moradi , Khodaberdi Kalavi , Mohammad Javad Kabir , Seyed Ahmad Hosseini , Danial Roshandel , Seyed Mehdi Sedaqat and Ahmad Danesh
  The aim of this study was to determine the seroprevalence of HCV in HBsAg positive subjects. In a population based single stage cluster sampling in Golestan province of Iran, 139 HBsAg positive subjects were detected and enrolled in the study. Serum samples were tested using ELISA method for anti-HCV antibodies. Chi-square and Fisher`s exact tests were used to compare the proportions. There were 68(48.9%) male and 71(51.1%) female. The mean age was 41.89±11.30 years (25-64 years). One case was excluded because of inadequate blood sampling. Anti-HCV antibody was positive in 17(12.3%) of 138 remaining subjects. Seropositivity of HCV in female was higher than male (14.1% versus 10.4%, respectively) but the difference was not statistically significant (p = 0.52). No significant relationship was seen between Anti-HCV seroprevalence and demographic factors such as age, place of residence and marital status. The seroprevalence of co-infection with HBV and HCV in our study was higher than such reports from some countries (Italy); but it was in line with worldwide prevalence (>10%). A careful longitudinal evaluation of the viremia levels of both HBV/HCV viruses is essential for making a correct diagnosis and tailoring the appropriate therapeutic schedule in co-infected patients.
  Abdolvahab Moradi , Amir Hossien Mohagheghi , Shahram Shahraki , Abasalte Borji , Abdoljalal Marjani , Esmaeil Sanei-Moghadam , Khoda-Berdi Kalavi and Mehdi Zangi-Abadi
  Present survey basically focused on women between 15-45 years of age resident in a town of Sistan and Baluchistan province named as Saravan city located in border of Pakistan-Iran in order to find out the seropositivity against the viruses in child bearing ages in the above stated under study community. This descriptive cross-sectional study was carried-out from 2001 up to 2002. Saravan town was divided into 4 geographical areas and each area was further sub-divided into 10 blocks and in each block 10 families were chosen randomly. In the next step by referring to each family from the chosen married women with specified age i.e., 15-45 years, 5 mL blood was collected. Serum was then separated and stored at -20°C before the assay. ELISA kit was employed to detect anti B19, anti rubella, anti measles, anti HBV and anti HCV antibody. Furthermore during samples collection a questionnaire filled for each woman under study. This study showed that 89.6% of women understudy were seropositive against measles, rubella (96.2%), B19 (59.2%), HCV (0.8%) and HBV (19.8%), respectively. According to the results of no serious problem with rubella in this area; But, about measles, the present immunity against measles in this area is insufficient. It seems that incidence of B19 infection in this region is same as other places in Iran. The rate of seropositivity against HBV and HCV indicated of these viruses circulating in the population in this area.
  Ezzat Ollah Ghaemi , Azad Reza Mansourian , Ali Reza Ahmadi , Mohsen Saeidi , Abdolvahab Moradi and Naser Behnampour
  Institutionalization of Mental Retarded (MR) children increase the risk of infections. In this study, we aimed at investigation the frequency of Streptococcus pyogenes, Brucella species and Salmonella species, infection among children with mental retardation living in Golestan Province in North of Iran. The study included 304 MR and 302 Healthy subjects who comprise the control group. ASO, Wright, 2ME, Widal and CRP were investigated in all serum samples, using Agglutination method. ASO positive test were 24.9 and 18.7% and the frequency of positive Wright test were determined 3.6 and 0.7% in MR and healthy children, respectively. Neither of the children in 2 groups has positive Widal test. The CRP positive test in MR children which was 4.9% were more than healthy children. The high frequency of streptococcal infection suggests that mental retarded children in our region need particular attention about the development of post-streptococcal infectionsequel.
  Iraj Shahramian , Abdolvahab Moradi , Malek Rakhshani , Abbas-Ali Moein and Mahin Badakhsh
  At the present time heroine dependency is treated by methadone. In order to determine the effectiveness of another medicine named buprenorphine, an interventional study has been carried out. In this interventional study of 70 patients, we compared buprenorphine (2 mg) and low dose (20 mg) methadone as treatment for heroine dependence. Buprenorphine and methadone were administered daily for 15 days. There were 35 patients in each group. Comparison between groups for withdrawal sign and symptoms showed no significant differences. As compared with low-dose methadone and buprenorphine, it was shown that buprenorphine is a suitable treatment fore heroine addiction in term of decreased withdrawal sign and symptoms.
 
 
 
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