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Articles by Abdolreza Sotoodeh Jahromi
Total Records ( 6 ) for Abdolreza Sotoodeh Jahromi
  Parvin Zareian , Abdolreza Sotoodeh Jahromi , Fateme Hemati Rad and Safar Zarei
  Problem statement: The purpose of this study was to evaluate the role of resistin and Tumor Necrosis Factor-α (TNF-α) in insulin resistance during pregnancy. Approach: Serum resistin and TNF-α concentrations were measured by ELISA in 86 healthy pregnant women (26, 23 and 37 of them in the 1st, 2nd and 3rd trimesters, respectively) and in 21 healthy non pregnant women in a cross sectional study. Results: Resistin concentration was significantly higher in the third trimester (9.5±3.3 ng mL-1) as compared with non pregnant women (7±3.3 ng mL-1). Serum TNF-α level were also significantly increase in pregnant women (2.6±1.9 pg mL-1) as compared with maternal healthy controls (0.8 ±0.7 pg mL-1). There were significant correlation between gestational age and BMI (r = 0.28, p = 0.01), resistin (r = 0.36, p = 0.002) and TNF-α (r = -0.44, p<0.0001). There was not significant correlation between gestational age and Insulin Resistance (IR). We also did not found correlation between IR and resistin as well as between IR and TNF-α in pregnant women. Conclusion: TNF-α and resistin do not appear to contribute greatly to pregnancy induced insulin resistance in healthy pregnancy.
  Abdolreza Sotoodeh Jahromi , Rahim Raoofi , Marzieh Sarikhani and Abdolhossain Madani
  Problem statement: The incidence of infectious diseases is increased in patients with chronic renal failure. Chronic renal failure severely influences the immune functions of the host. Approach: To evaluate the antitetanus immunity level in southern Iranian patients with end stage renal disease undergoing hemodialysis and to find its association with sex, age, blood hemoglobin and serum albumin, duration of dialysis. This cross sectional study was carried out on a total of 52 patients, who were on hemodialysis and 52 age and sex matched healthy individuals with without any underlying renal disease as a control group. Individuals in the both groups receiving antitetanus toxoid vaccine or immunoglubins a year prior to the study were excluded. The serum antitetanus IgG antibody levels were measured by an ELISA method. Results: Tetanus protected individuals in the patients and the control groups were 34.6 and 63.30% respectively. Of the evaluating factors just hemodialysis duration found to affect on tetanus immunity. Conclusion: Tetanus protected individuals in the patients group were significantly less than tetanus protected individuals in the control group (p = 0.011). Hemodialysis duration has significant effect on antitetanus immunity level.
  Abdolreza Sotoodeh Jahromi , Mahin Jamshidi Makiani , Mohammad Reza Farjam , Abdolhosin Madani , Malihe Amirian , Tasnim Eqbal Eftekhri and Sima Hamidipour
  Problem statement: Fetal loss and abortion are responsible for significant emotional distress for couples desiring children. There are many documents which support the role of some certain asymptomatic infections such as Cytomegalovirus (CMV) in spontaneous abortion. This study was aimed to evaluate the prevalence of seropositivity for CMV IgG and IgM in women with abortion and compare it with normal women with no previous history of abortion. Approach: This case-control study was carried out in Shariatee hospital of Hormozgan University of medical sciences, during 2003-2004. A number of 250 women with definite diagnosis of previous abortion and 200 matched women with normal full term delivery and negative history of miscarriage as controls were studied as case and control groups. Serum samples were obtained from participants and a demographic questionnaire was also filled for each of them. .All serum samples were then tested using ELISA method for detection of anti-CMV IgM and IgG Antibodies. Data was analyzed, using SPSS software (chi square and t-test). Results: The average age was 25.6±7.6 years in case group and 25.3±6.5 years in control group. The number and percentage for CMV-IgG was 235(94%) and 150(75%) in case and control groups, respectively (p-value = 0.0001). In case group 13(5.2%) women were positive for CMV-IgM, while no positive sample was detected in control group (p-value = 0.0001). Conclusion: This study showed higher prevalence of seropositivity for CMV in women with spontaneous abortion comparing to women with normal full term delivery and suggest that cytomegalovirus plays a significant role in abortion.
  Kavous Solhjoo , Abdolreza Sotoodeh Jahromi and Ayeh Parnian-Rad
  Problem statement: In situations of immunodeficiency, Toxoplasma gondii emerges as a life-threatening infection. Toxoplasma gondii is transmitted parenterally, flourish in immunocompromised subjects and, most toxoplasma infections are asymptomatic. Studies have shown that there is a immunodeficiency in renal failure patient such as hemodialysis patients and these patients have a high risk for many infections. There is no evidence about toxoplasmosis in hemodialysis patients in Iran. Approach: In the present study, we aimed to investigate the prevalence of anti-T. gondii antibodies in hemodialysis patients with chronic renal failure. This case-control study was carried out on 44 hemodialysis patients and 44 healthy controls for the prevalence of anti-T. gondii antibodies by ELISA. Anti-IgG, IgM and IgA T. gondii antibodies positivity were found to be 26 (59.10%), 3 (6.80%) and 3 (6.80%) of the 44 hemodialysis patients, respectively and 16 (36.40%) of the 44 control subjects were Anti-IgG T. gondii antibodies positivity and all of control subjects were negative for Anti-IgM and IgA T. gondii antibodies. The difference between them was statistically significant (p = 0.032). In addition, an increase of the seropositivity rate was detected with increasing length of time on hemodialysis treatment, indicating a statistically significant difference between these 2 parameters (p<0.001). Results: These findings confirm a high prevalence of toxoplasma infection in hemodialysis patients and these patients are a risk group for toxoplasma infection. Results showed that 3 hemodialysis patients had an acute and active infection. Conclusion: Moreover, it is recommended that hemodialysis patients who are susceptible to toxoplasma infections should be identified by T. gondii IgG and IgM and/or IgA specific serological tests. Therefore, patients undergoing hemodialysis should be screened for toxoplasma before dialysis to prevent the dissemination of this infection through the hemodialysis procedure.
  Abdolreza Sotoodeh Jahromi and Karamatollah Rahmanian
  Hemophilus influenza type b (Hib) infection has a high morbidity and mortality rate especially in children less than 5 years of age. The incidence of Hib disease in Iran is not known and Hib vaccine is not included in the National Immunization Program. The aim of the present study was to investigate the level of antibody to Hib of children five years or younger living in Jahrom, Iran. Three hundred eighty six children 5 years or younger were selected by random sampling method. A blood samples were taken from those children. Anti-Hib IgG antibody (anti-PRP) level was determined in the serum by using anti-Hemophilus influenza IgG EIA kit (IBL, Germany). An anti-PRP antibody levels of 0.15 μg mL-1 and over were accepted as the natural immunity. The mean concentration of Hib antibody was 0.94±0.480 μg mL-1. Natural immunity was determined in three hundred and twenty six (84.5%) of the children. The proportion of natural immunity was increased from 64.9% among children = 12 month old to 95.2% in children aged 49-60 month (p<0.001). The exposure rate of children with Hib was higher than expected, even in children who were just a few months old. Present data revealed need to be introducing Hib conjugate vaccine in the National Immunization Programs.
  Athar Rasekh , Hojjatollah Karimi Jashni , Karamatollah Rahmanian and Abdolreza Sotoodeh Jahromi
  There is a rapidly growing trend in the consumption of herbal remedies in the developing countries. The aim of this study was to determine the effects of orally administered Date Palm Pollen (DPP) on the results of semen analysis in adult infertile men. Forty infertile men participated in our study. They were treated by Pollen powder 120 mg kg–1 in gelatinous capsules every other day, for two months. Before and at the end of therapy, the semen was collected after masturbation and sperm numbers, motility and morphology were determined. Our findings revealed that consumption of DPP improved the sperm count. The treatment was significantly increased sperm motility, morphology and forward progressive motility. Date palm pollen seems to cure male infertility by improving the quality of sperm parameters.
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