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Articles by Abdolmajid Taheri
Total Records ( 3 ) for Abdolmajid Taheri
  Abdolmajid Taheri , Daryoush Fatehi , Mohsen Mohammadi and Ayoob Rostamzadeh
  Apoptosis involves a particular type of cell death that plays an important role in tissue turnover and homeostatic regulation. Remove unwanted cells in multicellular organisms and unicellular organized by this process. Cell apoptosis begins with the production and release of various factors. The effects of apoptosis depend on the environment in which is occur programmed cell death. Apoptosis in some cells also causes release of various factors such as cytokines and subsequently mediated activation of other protein mediators of immune and inflammatory response. Today, using genes, inducer metabolites and inhibitors involved in of apoptosis, or programmed cell death, can be immune system (the balance between cellular and humoral immune) is directed towards the desired immune response. There are different methods for detection of apoptotic cells and each of these methods alone cannot be used as the criterion of apoptosis. The activation of caspases also is a marker for cellular damage in diseases. Caspases as an indicator is specific apoptosis therefore determine the activation of caspase can be used to differentiate between necrosis and apoptosis. Molecular imaging is ideally suited to measuring early response by quantifying cellular metabolism, proliferation and apoptosis, activities altered early in treatment. There are now several possible Magnetic Resonance Imaging (MRI) based approaches for detecting apoptosis, in particular tumor apoptosis, which have the potential to be translated into clinical application. Detection of cellular lipid droplet accumulation, using localized Magnetic Resonance Spectroscopy (MRS) and changes in tissue architecture using Diffusion-Weighted Imaging (DWI) has the virtues that they are completely non-invasive and thus could be implemented in the clinical practice now. Potential disadvantages include a lack of specificity for apoptosis and the possibility that they may be limited in detecting relatively low but clinically relevant, levels of cell death. Finally using labeled molecular factors and inducer proteins and also measurement of metabolites by non-invasive medical imaging techniques such as magnetic resonance spectroscopy can be identified the actual mechanisms and pathways of apoptosis as well by manipulated these pathways may be effective in the prevention of diseases such as autoimmune and neurodegenerative disorders.
  Abdolmajid Taheri , Hossien Masoumi , Ardeshir Moayeri and Ayoob Rostamzadeh
  Magnetic Resonance Spectroscopy (MRS) is a non-invasive diagnostic and is the neuroimaging method of choice for the noninvasive monitoring of brain metabolism in patients with glioma tumors due to the enormous amount of information it yields regarding the morphologic features of the lesion and surrounding parenchyma. The most prevalent metabolites in the MRS spectrum are N-acetylasparate (NAA), total-Cholinecontaining metabolites (Cho), Lactate (Lac), Mobile Lipids (Lip), Creatine (Cre), Glutamate (Glu), Glutamine (Gln; the glutamate and glutamine signals cannot always be resolved and studies will then refer to their composite Glx peak), Myo-Inositol (mIns), Glycine (Gly), Glutathione (GSH) and 2-Hydroxyglutarate (2-HG). Personalized medicine using MRS can be used an understanding of the various physiological basic and mechanism of the metabolic signatures obtained from different types of tumors, and the specificity of the technique. Finally, establishment basis of physiological characteristics of the metabolites in various types of brain tumors, and the clinical utility of MRS as an additional and confirming diagnostic tool could improvement processes include fact and correct primary differential diagnosis therapeutic planning, and the assessment of response to treatment.
  Abdolmajid Taheri , Mohammad Gharib Salehi , Farhad Naleini , Jamil Abdolmohammadi , Ayoob Rostamzadeh and Daryoush Fatehi
  This study evaluated the clinical usefulness of MRI ability in assessment of different stroke satege using routine and advance technique such as T2w, FLAIR, DWI and perfusion MRI. There are four stages of stroke which include hyper acute, acute, sub acute and coronic. Also there are four types of brain hemorrhages like, Epi Dural Hematoma (EDH), Sub Dural Hematoma (SDH), Intracerebral or Cranial Hematoma (ICH) and Sub Arachnoid Hematoma (SAH). Although, CT is a diagnostic routine for stroke but MRI can be valuable diagnostic imaging for representing information particularly in connection with hemorrhagic infarcts give us. Multimodal imaging provides information that is useful for diagnosing ischemic stroke, selecting appropriate patients for thrombolytic therapy and predicting the prognosis of ischemic stroke.
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