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Articles by A.Y. Faremi
Total Records ( 3 ) for A.Y. Faremi
  A.Y. Faremi and J.T. Ekanem
  The effect of Nigella sativa (black seed) oil based diet on the management of Trypanosoma brucei infected rats was investigated. Prasitaemia was monitored and haematological and enzymatic studies were carried out on liver and blood of infected rats fed with diet formulated with black seed oil (treatment). Comparison was made with untreated infected rats and uninfected rats. The diet formulated with black seed oil extended the life span for 7 and 5 days for prophylactic and early stage feeding, respectively while the late stage feeding extended it by a day. The T. brucei-infection significantly (p<0.05) increased liver Glutamate Oxaloacetate Transaminase (GOT), Glutamate Pyruvate Transaminase (GPT) and Gamma Glutamyl Transaminase (GGT). Serum GOT and GPT specific activities were also significantly (p<0.05) increased. However serum GGT activity showed no significant (p<0.05) difference in all the rat groups. While haemoglobin concentration, white blood cells, red blood cells, pack cell volume, mean cell haemoglobin concentration and platelet were significantly (p<0.05) reduced, as observed in the control and late stage feeding, by the infection, prophylactic and early stage feeding with diet formulated with N. sativa oil significantly (p<0.05) improved the parameters towards those obtained in uninfected rats. We concluded that the N. sativa oil used in formulated diet could be involved in the improvement of the pathologic events observed in the T. brucei infected rats with prophylactic and early stage feeding.
  A.Y. Faremi and O.B. Oloyede
  The effects of soap and detergent industrial effluents on some enzymes in the stomach of Albino rats (Rattus norvegicus) were investigated. Four concentrations (5, 25, 50 and 100% v/v) of the effluent were used as the main sources of water for four groups of rats over thirty days while feeding the rats ad libitum with a commercial rat chow such that the method of feeding did not constitute a variable. Tap water was used as the control water. The physicochemical characteristics of the effluents and tap water were determined and compared with WHO standard. The average life weight gain was measured at every fifth days. At the end of the experiment, the rats were sacrificed and activities of alanine amino transferase (ALT), aspartate amino transferase (AST), lactate dehydrogenase (LDH) and alkaline phosphatase (ALP) were monitored in the stomach of the rats as a means of assessing the biochemical implication of the consumption of the chemical effluents. Soap and detergent industrial effluents presented high level of Biochemical Oxygen Demand (BOD), chemical oxygen demand (COD), Total Dissolved Solids (TDS) and some heavy metals like Pb, Cd and Mn. There were significant (p<0.05) difference and effluent concentration dependent increase in the activity of ALT, AST, LDH while ALP activity showed an effluent concentration dependent decrease in the stomach of the rats. The results showed that the consumption of the water contaminated with soap and detergent industrial effluents may be involved in the stomach dysfunction.
  P.C.N. Alikwe , A.Y. Faremi and P.A. Egwaikhide
  The effect of various inclusion of rumen epithelial scraps as substitute for fish meal proteins on the feed intake, nitrogen retention, serum metabolites, enzymes and haematological parameters in broiler-chicks in their finisher phase were examined. Five set of meal with 0, 25, 50,75 and 100% inclusion of rumen epithelial scraps as substitute for fish meal proteins were formulated. About 100 days old chicks were fed a nutritionally sound starter mash for 4 weeks after which they were randomly divided into 5 groups and placed on the various formulated diets. The feed intake and the weight gain in each group was measured for the following 21 days after which the birds were sacrificed. Nitrogen retention, serum proteins, liver enzyme activities and haematological evaluation were carried out. The feed intake, nitrogen retention and the weight gain in broiler-chicks fed 75 and 100% RES inclusion diet were significantly (p<0.05) lower than those of broiler-chicks fed 0, 25 and 50% RES inclusion diet. The albumin/globulin ratio in broiler-chicks fed 100% RES inclusion diet was significantly (p<0.05) higher than those of broiler-chicks in other groups. Mean Cell Heamoglobin (MCH), Mean Cell Haemoglobin Concentration (MCHC) and Mean Cell Volume (MCV) in broiler-chicks fed 0, 25 and 75% RES inclusion diet were significantly (p<0.05) lower than those of broiler-chicks fed 50 and 100%, RES inclusion diet. However, neutrophils of broiler-chicks fed 0, 25 and 50% RES inclusion diets were significantly (p<0.05) higher than those of 75 and 100% RES inclusion diets. The Pack Cell Volume (PCV), Haemoglo bin Concentration (HBC), White Blood Cell (WBC), lymphocytes and monocytes compared favourably in all the groups. The liver alanine transaminase and aspartate transaminase acivities in all the groups examined compared favourably. It infered that the 25 and 50% RES inclusion as substitute for fish meal protein could be employed to maintain the quality of the broiler-chicks while minimizing the high cost of whole fish meal since RES is an abattoir by-product that is available locally.
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