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Articles by A.S.M. Anisuzzaman
Total Records ( 2 ) for A.S.M. Anisuzzaman
  M.S. Hossain , M.R.I. Khan , A.S.M. Anisuzzaman , M. Ahmed , M.S. Amran and A. Islam
  Diabetes is a major public health problem. The development of new therapies that are able to improve glycemia management and even to cure diabetes is of great interest. The antihyperglycemic activity of leaves of Mangifera indica was evaluated with scientific approaches. The study was undertaken to investigate the antihyperglycemic, Oral Glucose Tolerance Test (OGTT) and glycogenesis effects of the different fractions (Petroleum ether, ethyl acetate and chloroform) of ethanolic extract of Mangifera indica. The different extracts were administered intraperitoneally as a single dose of 150 mg kg-1 b.wt. to normal, glucose induced and alloxan induced diabetic rats and found to reduce blood glucose level significantly (p<0.05). Beside these, the different fractions of Mangifera indica to the alloxan-induced diabetic rats resulted in the significant elevation of liver glycogen content which was decreased by 50.60% in diabetic control. The effects of plant extracts were compared with standard drug metformin. The phytochemical screening tests indicate the different constituents such as triterpines, alkaloids, flavonoids etc. are present in the plant which have the antidiabetic property. Thus, this investigation paves the way for plant based diabetic treatment and indicates that various fractions (Petroleum ether, ethyl acetate and chloroform) of the ethanolic extract of Mangifera indica have favorable effect in bringing down the severity of diabetes as well as increase glycogenesis activity by increasing the cellular uptake of glucose.
  Bytul M. Rahman , M.S.A. Bhuiyan , M.A.A. Al-Bari and A.S.M. Anisuzzaman
  This investigation was an attempt to determine the primary selection of the compounds as therapeutic agents, isolated from an antagonistic Streptomyces species. The antimicrobial metabolites were extracted by CHCl3 from the fermentation broth of organism. The antimicrobial activity profile of the crude metabolites (M) as well as two isolated compounds (BM-3 and BM-5) from the crude metabolites, was interesting against some pathogenic bacteria. The minimum inhibitory concentration (MIC) of the crude metabolite (M) and compounds against six pathogenic bacteria was found to be between 16 and 64 Fg ml-1 respectively.
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