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Articles by A.O. Adejuwon
Total Records ( 5 ) for A.O. Adejuwon
  A.O. Adejuwon and C.A. Adejuwon
  In the present study endocervical swabs from women classified in three groups were taken. The groups were women who had been on intra-uterine contraceptive devices for at least two months and experiencing vaginal discharge noticed visibly or through the use of speculum (n=16); first control subjects which were women who had been on intra-uterine contraceptive devices for at least two months but not experiencing vaginal discharges (n=14) and a second control subjects which were women who had never been on contraception (n=2). Candida albicans, Neisseria gonorrhea, Klebsiella species and Escherichia coli were pathogens isolated within the experimental group (n=16). Lactobacilli and Candida albicans were isolated in the first control subjects (n=14). No microbial growth was observed within subjects of the second control group (n=2). Statistical analysis indicated that only 25% of the experimental subjects showed evidence of infection while 14.3% of women within the first control subjects (n=14) were infected. Since the establishment that infection occurring in less than one month of intra-uterine contraceptive device implant can be meaningfully ascribed to the presence of the intra-uterine contraceptive device, it is recommended that cases of women implanted with intra-uterine contraceptive devices, experiencing vaginal discharges and irritation should be thoroughly investigated before prescription of drugs by physicians.
  A.O. Adejuwon , C.A. Adejuwon , O.K. Awojobi and O.E. Olasunkanmi
  Magnesium was detected in the human plasma of individuals (n = 20) with various kidney diseases and having gonorrhea. The values were relatively higher than those of controls (n = 20) (individuals without kidney diseases and without infection with Neisseria gonorrhea or any other veneral disease). Two of the individuals within the control group had plasma magnesium concentrations below 0.9 mg per 100 mL. The other eighteen individuals had values within the range of 0.9-1.9 mg per 100 mL. None of the infected patients with kidney disease had plasma magnesium concentration below 0.9 mg per 100 mL. All infected females with kidney diseases had plasma magnesium concentration above 1.9 mg per 100 mL. Of the total infected males, with various kidney diseases, 35% had plasma magnesium concentrations above 1.9 mg per 100 mL. Inspite of the fact that gonococal infection affects the upper renal tract, there seems to be no significant effect of such infection on plasma hypermagnesemia in individuals with certain kidney diseases. Hypermagnesemia could therefore still be a problem in patients with gonococal infection accompanied with renal diseases.
  C.A. Adejuwon and A.O. Adejuwon
  Serum levels progesterone and testosterone were measured by radioimmunoassay (RIA) in female and male mice infected with Plasmodium berghei berghei, respectively and in uninfected female and uninfected male mice correspondingly. The mean SEM serum progesterone (nmol L-1) of 2.41±0.31 in infected female mice is lower than 3.45±0.44 observed in uninfected mice. The mean SEM serum testosterone (nmol L-1) of 2.24±0.2 in infected male mice is significantly higher than 1.39±0.14 observed in uninfected mice. The results provide evidence to suggest that malaria parasite Plasmodium berghei berghei lowers peripheral levels of progesterone in female mice. However, it appears to increase peripheral levels of testosterone in male mice. Malaria is known to be an endemic disease of the tropics. In females, the actions of progesterone as an antagonist to both sodium retaining and potassium losing effect of adrenal steroids could be affected. Raised levels of testosterone in males during infection could possibly reduce the risk of aplastic anaemia in the young approaching puberty.
  A.A. Ajayi , A.O. Adejuwon , O.K. Awojobi and P.O. Olutiola
  Within ten days of incubation, freshly ripe tomato fruits (Ibadan local variety) obtained from a local market in Ile-Ife, Osun State, Nigeria had completely deteriorated and proteins which possessed cellulolytic activity were released. The enzyme was partially purified by a combination of ammonium sulphate precipitation, molecular exclusion chromatography and ion-exchange chromatography. The enzyme was stimulated to varying degrees by Ca++, Mg++, Na+ and K+ but was inhibited by ethylene diamine tetraacetic acid, 2, 4-dinitrophenol and mercuric chloride.
  A.O. Adejuwon and P.O. Olutiola
  Tomato fruits infected with Fusarium oxysporum produced proteins which exhibited proteolytic activity. The enzyme was partially purified by molecular exclusion and ion-exchange chromatography. Two components with molecular weight estimates of approximately 112, 000 and 63,100 were expressed. The enzyme exhibited maximum activity at pH 6.0 and 35°C. It possessed an apparent Km of approximately 4.3 mg mL-1 for casein. The enzyme was stimulated by the monovalent cations, Na+ and K+ and by the divalent cations; Mg++ and Ca++ but inhibited by ethylene diamine tetra acetic acid and mercuric chloride.
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