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Articles by A.M. Okafor
Total Records ( 3 ) for A.M. Okafor
  E.U. Madukwe , A.M. Okafor and V.U. Ogbonna
  This study evaluated effectiveness of fresh and shade-dried Mucuna pruriens leaf extract in managing anaemia in adult male albino rats. Fresh leaves of Mucuna pruriens were harvested from Enugu-Ezike, Enugu state, Nigeria. The leaves were used to prepare fresh and shade-dried leaf extracts which were subjected to chemical analysis using standard analytical methods. Fifteen adult male albino rats weighing 180-250g, grouped into three groups (A, B and C) of five rats each were used for the study. All groups received rat chow and water ad-libitum. Group B and C received in addition, the fresh and shade-dried Mucuna pruriens leaf extracts respectively after anaemia induction. Blood samples were collected from the rats for determination of haemoglobin, PCV, RBC and WBC after a 5-day acclimatization, after anaemia induction and at the end of the study. Statistical Package for Social Sciences (SPSS) for windows version 18 was used to analyze the data obtained. p<0.05 was accepted as a cut-off for significant level. Fresh and shade-dried Mucuna pruriens leaf extracts contained iron (9.00±0.28 and 3.50±0.00 mg/100 mL), vitamin C (18.45±2.19 and 31.35±0.35 mg/100 mL) and pro-vitamin A (100.21±0.28 and 170.21±0.28 mg/100 mL). Haemoglobin, packed cell volume and white blood cell of rats fed fresh Mucuna pruriens leaf extract significantly (p<0.05) increased after treatment. Shade-dried Mucuna pruriens leaf extract significantly (p<0.05) increased red blood cell and white blood cell of the rats after treatment. Lymphocytes of the anaemic rats fed fresh and shade-dried Mucuna pruriens leaf extracts was significantly (p<0.05) increased whereas there was no significant (p>0.05) increase in the eosinophils of the anaemic rats.
  E.U. Madukwe , A.M. Okafor and C.M. Enemkpali
  This study assessed effect of Iresine herbstii leaf extract and powder on biochemical profile of adult male albino Wistar rats. Twenty adult male albino Wistar rats divided into four groups of five rats each were used for the study. All the animals received rat-chow and water ad-libitum. Group A was the control. Groups B, C and D received in addition, fresh leaf extract, shade-dried leaf extract and shade-dried leaf powder, respectively. Blood samples were obtained from the rats for lipid profile, liver and kidney function tests. Data obtained were analyzed using Statistical Package for Social Sciences (SPSS) for windows version 18. p<0.05 was accepted as level of significance. Serum AST was significantly (p<0.05) increased in rats fed fresh leaf extract. There was a significant (p<0.05) reduction in serum ALT of rats fed shade-dried leaf extract and powder. However, serum ALT of rats fed fresh leaf extract was significantly (p<0.05) increased. Serum ACP was significantly (p<0.05) increased in the three treatment groups. Serum creatinine was significantly (p<0.05) increased in rats fed fresh leaf extract. Rats fed shade-dried leaf powder showed a significant (p<0.05) increase in serum urea after treatment. Serum urea of rats fed fresh leaf extract was slightly reduced. There was a significant (p<0.05) increase in total cholesterol of rats fed fresh leaf extract whereas rats fed shade-dried leaf powder showed a significant (p<0.05) decrease in total cholesterol. Serum LDL-C of three treatment groups were increased. However, this was only significant (p<0.05) in rats fed shade-dried leaf extract.
  A.M. Okafor , E.O. Odo and E.O. Onodigbo
  Background and Objective: A lack of dietary diversity is a qualitative reflection of inadequate nutrient(s) in the diet of individuals. This study was conducted to assess dietary diversity and its association with academic performance and anthropometric indices of primary school children (6-12 years) in Ukehe, a rural community in Nsukka, Nigeria. Materials and Methods: A multistage random sampling technique was used to select 522 respondents. Dietary diversity was assessed using the 2010 Food and Agriculture Organization guidelines for measuring individual dietary diversity. Academic records of the children were used to assess their academic performance. Anthropometric measurements of the respondents were obtained using standard procedures. Data were analyzed using the computer software package Statistical Product and Service Solution (SPSS). Significance was accepted at p<0.05. Results: Some (30.3%) of the respondents had low dietary diversity scores, whereas most (54.8%) had an average academic performance. Some (31.8%) of the respondents who were in the medium dietary diversity category also had an average academic performance. Stunting was present in 4.4% of the respondents, 5.0% were underweight and 3.4% were wasted. Dietary diversity was positively associated with academic performance and anthropometric indices. Conclusion: Medium dietary diversity and an average academic performance were recorded for most of the respondents. Low prevalence of stunting, wasting, underweight and overweight existed among the respondents.
 
 
 
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