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Articles by A.C. Omonhinmin
Total Records ( 3 ) for A.C. Omonhinmin
  Omolola E. Omotosho , A.C. Omonhinmin , S.O. Rotimi , E.E.J. Iweala , O.A. Rotimi and Ayoade Femi
  The aim of this study is to partially purify and characterize the cellulase extracted from the snail haemolymph of the African giant land snail of the species, Archachatina marginata. The protein concentration of the haemolymph was found to be 168 mg mL–1 and the specific activity of the crude cellulase was found to be 0.007 U mg–1 protein using Carboxymethyl-cellulose (CMC) as the substrate. The partial purification on Sephadex G-200 produced two activity peaks. The molecular weights of the two cellulase fractions were estimated to be 112,202 and 67,000. The Michealis Menten constant (km) for cellulase was 4.3 and 2.8 mg mL–1 for the higher and lower molecular weight fractions, respectively. The multiplicity of cellulase complexes indicated that the haemolymph of A. marginata may convert derived cellulose in foodstuffs such as garlic, mushrooms and domestic wastes into sources of fuel. It is suggested that the enzyme can be used to produce value-added products, such as ethanol, citric acid, amino acids and vitamins including primary metabolites from cellulosic wastes.
  M. Idu , A.C. Omonhinmin and H.I. Onyibe
  The phenology, seed germination, seedling development and evaluation were carried out on the seeds of Hura cepitans. The phenological data describes Hura crepitans seeds as 0.94 g in weight, 2.3x2.2x.48 cm in size; 3.6 cm3 mean volume, of 78% moisture level. The capsule of length 8 cm contains 7-16 seeds. The seeds are circular in shape, smooth, glabrous and glossy in texture with a capsule depth of 2.5 cm and a brownish testa. The plant flowers and fruits from the end of October to the end of June. To break dormancy, investigations on the stimulatory effect of chemical scarifications were analyzed. Methanol pre-treatment recorded the highest of 70% germination. Comparatively, some of the pretreatments showed better germination energy and vigour than the control. Such pretreatments are good for germination and nursery establishment of the species.
  A.C. Omonhinmin , I.P. Dike and S.O. Rotimi
  The study investigated the phytochemical, cytotoxicity and antioxidant properties of Allamanda cathartica (AC), Bixa orellana (BO), Cymbopogon citratus (CC), Ficus exasperata (FE) and Momordica charantia (MC) used traditionally for the anti-malarial preparations "Agbo" in Nigeria. Phytochemical screening of the plants showed the presence of flavonoids, terpenoids, phenolics, cardiac glycosides and reducing sugars. Free radical scavenging activity of the plants with 2, 2-Diphenyl-1-Picrylhydrazyl (DPPH) recorded significant IC50 values for the inhibition of DPPH by ethanolic leaves extracts of AC (0.46), BO (0.45), CC (1.35) and FE (0.86), respectively and Vit. E (control), recorded higher activity at 0.5 mg mL-1 with an IC50 of 0.25 μg mL-1. BO leaf extracts recorded the most potent effect (0.45) at low concentration of 0.5 mg mL-1. The free radical scavenging activities of these plants doubtlessly contribute to their use in indigenous malaria therapy and may qualify them for anti-malarial drug screening.
 
 
 
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