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Articles by A.B. Aliyu
Total Records ( 4 ) for A.B. Aliyu
  A.B. Aliyu , M.A. Ibrahim , A.M. Musa , T. Bulus and A.O. Oyewale
  Leaf extract and fractions of Vernonia blumeoides were evaluated for total phenolics content (Folin-Ciocalteu method), free radical scavenging activity (1, 1-diphenyl-2-picrylhydrazyl radical assay), total antioxidant capacity (Phosphomolybdate assay) and ferric reducing power. The results of the phenolics content expressed in mg/100 g of Gallic Acid Equivalent (GAE) showed that the n-butanol fraction has significantly (p<0.05) higher phenolics content (410±0.8) than the chloroform fraction and ethanol extract. The radical scavenging activity of the extract and solvent fractions displayed strong concentration dependent activity. But it was also observed that the ethyl acetate fraction showed highest activity in all concentration tested ranging from 70.56 to 99.04%. However, the total antioxidant capacity (mg g-1 ascorbic acid) showed that n-butanol fraction has the highest capacity (60.0 mg g-1). The results also showed that the n-butanol extract has strongest reducing ability (2.105±0.109 nm) at higher concentration which is comparable to that of Gallic acid at all the concentrations tested. Phytochemical screening on the extracts revealed the presence of flavonoids, saponins and tannins. The results suggest that the plant especially the n-butanol and ethyl acetate fractions are very rich in antioxidant compounds worthy of further investigations.
  A.M. Musa , G. Abbas , A.B. Aliyu , M.S. Abdullahi and I.N. Akpulu
  Antimicrobial activities of the crude methanol extract as well as the n-butanol and residual aqueous fractions from the aerial part of Indigofera conferta used in traditional medicine to treat infected wound were investigated using disc diffusion and broth dilution techniques. The extract and the fractions were tested against Staphylococcus aureus, Bacillus subtilis, Pseudomonas aeruginosa, Escherichia coli and Candida albicans using Ampiclox as standard antibiotic. The crude methanol extract and the aqueous fraction exhibited activity against all the organisms tested (zones of inhibition 16-34 and 14-31 mm, respectively). The n-butanol fraction showed activity on Staphylococcus aureus, Bacillus subtilis and Pseudomonas aeruginosa only (zones of inhibition 14-25 mm). Phytochemical screening on crude extract revealed the presence of tannins, flavonoids and steroids. This study showed that the leaves of Indigofera conferta contains active compounds and its antimicrobial activity justifies its use in traditional medicine.
  M.B. Tijjani , I.A. Bello , A.B. Aliyu , T. Olurishe , S.M. Maidawa , J.D. Habila and E.O. Balogun
  Methanol extract of the root of Cochlospermum tinctorium was evaluated for antibacterial activities using hole-in-plate bioassay technique against Escherichia coli, Staphylococcus aureus, Klebsiella pneumoniae, Corynbacterium ulcerans, Proteus mirabilis and Shigella dysentriae using ciprofloxacin (10 μg mL-1) and gentamicin (10 μg mL-1) as reference standards. The extract was active on all the test organisms at concentration of 2000 μg mL-1. The activity of the extract against S. dysentriae was found to be more potent with MIC 100 and MBC 500 μg mL-1. Time kill studies showed that the antibacterial activities were time dependent. Phytochemical screening revealed the presence of alkaloids, flavonoids, tannins and cardiac glycosides. These phytochemicals could be responsible for the antimicrobial activities exhibited by the extract and hence justify the ethnomedicinal uses of C. tinctorium.
  A.B. Aliyu , A.M. Musa , M.S. Sallau and A.O. Oyewale
  Biochemical studies with a view to assess the nutritional potentials of Anisopus mannii were carried out by evaluating the proximate composition, mineral elements and anti-nutritional content of the plant. The results showed that the total oxalates, free cyanides, tannins and total cyanides were found to be present at 0.70 ± 0.5, 6.50 ± 0.41, 10.55 ± 0.01 and 12.41 ± 7.19%, respectively. However, concentration of phytate was very low (0.017 ± 0.00%). Proximate compositions of the plant showed a rich source of crude protein (8.40 ± 0.17%), fats (8.67 ± 0.63%), carbohydrates (72.57 ± 0.68%) and total ash (10.36 ± 0.22%). The plant was also found to contain the following essential minerals: potassium (1700 mg/100 g), calcium (1280 mg/100 g), iron (156 mg/100 g), vanadium (102 mg/100 g), chromium (53.90 mg/100 g), zinc (0.874 mg/100 g), copper (1.43 mg/100 g) and manganese (36.60 mg/100 g). The results of this research indicated that Anisopus mannii has nutritional qualities that could provide the users with additional nutrients for enhanced curative process of ill health.
 
 
 
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