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Articles by A.A. Odutuga
Total Records ( 5 ) for A.A. Odutuga
  O.B. Oloyede , A.A. Odutuga , J.B. Minari and A.A. Amballi
  Sixty day-old broiler chicks were used in a 4-weeks feed trial to determine the status of raw, roasted and fermented bambara groundnut. The raw and processed bambara groundnuts were used as the sole source of protein in a basal broiler chick starter diet. Soybean based diet served as the control. There were four (4) experimental groups each made up of five birds in three replicates, allocated to the experimental diets. Application of roasting and fermentation techniques were able to reduce the levels of some antinutrients in the bambara groundnut except for oxalate that increased significantly for the fermented sample. The results showed that the serum parameters like total protein, uric acid and creatinine levels indicated that both roasted and fermented based diet fed to the birds were unable to efficiently make available the nutrients in the diets to the birds. Serum transaminases (GOT and GPT) and serum alkaline phosphatase (ALP) showed significant (p<0.05) increase in the activity of the serum of birds fed on roasted and fermented bamabara groundnut based diet. It is therefore concluded that the quality of the protein of the raw and processed bambara groundnut based diet demonstrated inferiority relative to the soybean based diet.
  A.A. Odutuga , F.A. Bamisaye , A.A. Amballi and G.B. Adebayo
  The effects of three isocaloric leguminous based diets on the digestibility of neutral lipids and phospholipids in albino rats were investigated. Proximate analyses of each of the beans and formulated diets were carried out to determine crude protein, crude fat, crude fibre, total ash, moisture and carbohydrate contents. A total of thirty (30) albino rats (Rattus norvegicus) were used for the study. The rats were divided into three groups of ten rats each and maintained on Soyabean-Based Diet (SBD) (Control), Cowpea-Based Diet (CBD) and Hyacinth Bean-based Diet (HBD) for a period of five weeks. At the end of the experiment, the brain, liver, heart and the kidney of the rats were isolated and the neutral lipids and phospholipids contents of each organ were estimated. Rats maintained on Cowpea-Based Diet (CBD) had the lowest weight gain when compared with those fed on the HBD and SBD respectively. The results revealed that the neutral lipids and phospholipids of CBD show a significantly reduced (p<0.05) digestibility than HBD and SBD. The significantly reduced (p<0.05) digestibility of lipids in CBD may be considered to be partly responsible for the lower growth rate of rats maintained on this diet.
  A.A. Odutuga and A.A. Amballi
  The effects of dietary saturated fat on blood lipid and lipoprotein composition and lipid peroxidation were studied in rats. Male albino rats (Rattus norvegicus) were maintained either on diets with 5% fat supplements made of 5% soyabean oil or 5% coconut oil. Similarly, two other groups were fed diets that were isocaloric with the former but contained 25% fat supplements made of 25% soyabean oil or 25% coconut oil. The concentration of triacylglycerols in the plasma of the high coconut oil fed rats was three to six-times those of the others. The concentration of free cholesterol was much higher in the plasma of the coconut oil-fed rats. There were significant decreases in the plasma level of chylomirons, VLDL and HDL, but a significant increase in the LDL level of the coconut oil-fed rats. In all the tissues studied, the malondialdehyde level increased significantly in the coconut oil fed rats and most prominently in the liver and the kidney, while the reduced glutathione levels decreased significantly in the coconut oil-fed rats. It is considered that ingestion of coconut oil for a considerably long time may affect lipid metabolism and alter the structure and function of the enzymes responsible for converting the essential fatty acids to prostaglandins or their endoperoxide precursors. The increase in the malondialdehyde level and the decrease in the reduced glutathione level are indications of the lipid peroxidative effect of saturated fat diet, while the reduced HDL and high level of LDL can be major contributory factors to atherogenesis.
  J.B. Minari , A.A. Odutuga , F.A. Bamisaye , J.O. Dairo and B.S. Fagbohunka
  The effects of some processing technique on the proximate and antinutritional factors in Leucaena leucociphala seed were evaluated. The crude protein, ether extract, crude fibre, ash content and nitrogen free extract were estimated on raw, roasted and cooked samples of Leucaena leucociphala milled seed. The antinutritional factors such as phytate and tannin were also determined in the raw and processed samples of the seed. The nitrogen free extract of the raw sample was observed to be significantly lower (p<0.05) compared to those of roasted and cooked samples. A significant increase (p<0.05) was observed in the ether extract and crude fibre of raw sample compared with that of roasted and cooked samples. A significant reduction (p<0.05) was observed in the level of phytate of roasted and cooked samples compared to the raw sample. A significant reduction (p<0.05) was also observed in the level of tannin of cooked sample compared to raw and roasted. The study revealed that there was improvement in the nutritional quality of the processed seed with reduction in the antinutritional factors.
  A.A. Odutuga , J.O. Dairo , J.B. Minari and F.A. Bamisaye
  The present study was undertaken to investigate the potential hypoglycemic effect of aqueous and methanolic extracts of M. lucida stem bark in alloxan-induced hyperglycemia in rats. The study comprises three groups of diabetic rats administered 0.240 mg (aqueous extract) and 240 mg (methanolic extract) kg-1 body weight and a fourth group given 10 mL kg-1 body weight distilled water for 7 days. Body weight, fasting blood glucose as well as activities of some selected serum and liver enzymes were monitored before commencement of treatment and at the end of the treatment period. At the end of the 7 day treatment, fasting blood glucose of the animals were significantly (p<0.05) reduced by 73.5 and 39.0% of their initial values in diabetic group administered aqueous and methanolic extract, respectively. As it were before treatment, body weight was further reduced in the diabetic animal groups compared to normal rat group. Serum Alkaline Phosphatase (ALP) and liver aspartate Aminotransferase (AST) activities were not significantly (p>0.05) altered from their initial values after the 7 day treatment period. Serum AST and liver ALP were significantly (p<0.05) lowered in diabetic rats treated with aqueous and methanolic extracts compared to their initial values. Serum and liver Alanine aminotransferase (ALT) activity was significantly (serum)/non-significantly (liver) increased across the groups except for a significant decrease observed in liver ALT activity in diabetic rats administered the methanolic extract.
 
 
 
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