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Articles by A.A. Abena
Total Records ( 3 ) for A.A. Abena
  N. Okemy-Andissa , J.M. Ouamba , J. Koudou , M. Diatewa , M Gbeassor and A.A. Abena
  Aqueous extract of an association of Ageratum conyzoides (Ac), Combopogon citratus (Cc) and Lippia multiflora (Lm) produced a significant reduction in mouse of writhings induced by acetic acid and an increase of pain threshold in the hot plate test in mice. These effects were similar to that produced by the traditional improved preparation Tetra? which is prepared with twenty plants, among them, Ac, Cc and Lm. On contrary of morphine, analgesic activities of the extract association and Tetra? is not inhibited by naloxone. Chemical study revealed the presence in the two preparations of saponins and flavonoids which could support the observed activities. These results suggests that, this association of three plants could be used as traditional improved preparation in the aim to minimise the important number of plants in Tetra?.
  J. Koudou , A.W. Etou Ossibi , K. Aklikokou , A.A. Abena , M. Gbeassor and J.M. Bessiere
  The composition of the essential oil from the fruit seeds of Monodora myristica Gaertn. (Annonaceae) was studied by capillary gas chromatography. The analysis using a combination of retention indices and combined Gas Chromatography/Mass Spectrometry (GC/MS) led to the identification of 30 components. The oil contains mainly monoterpenoids (93.2%) out of which 77.4% are monoterpene hydrocarbons and some sesquiterpenoids (5.8%) The major constituents were α-phellandrene (34.4%) and p-cymene (22.2%). The essential oil effects on the cardiovascular system were studied by recording the amplitude and frequency of the frog isolated heart contractions and by recording arterial blood pressure variations of the guinea pig. At the dose of 40, 80 and 120 μL kg-1 the essential oil induced a hypotensive effect on the blood pressure and at the dose of 0.01-0.05%. It reduced significantly the cardiac contractions of the isolated heart; however at 0.06% it totally stopped the cardiac contractions. Both these effects conducted in the present study could contribute to the anti hypertensive activity of the Monodora myristica essential oil.
  N. Okiemy-Andissa , M.L. Miguel , A.W. Etou , J.M.Ouamba , M. Gbeassor and A.A. Abena
  Analgesic effect of aqueous and hydroalcoholic extracts of aeral parts of Hyptis suavolens, Nauclea latifolia and Ocimum gratissimum, three plants used in congolese folk medicine in pain, were tested on acetic acid and hot plate tests. All extracts manifest analgesic effect on the two models used. The more active was the hydroalcoholic extract of Ocimum gratissimum which is not antagonized by naloxone and could potentiate analgesic effect of paracetamol.
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