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Articles by A. Roy
Total Records ( 5 ) for A. Roy
  G. Martinotti , V. Carli , D. Tedeschi , M. Di Giannantonio , A. Roy , L. Janiri and M. Sarchiapone

The study aimed to examine the clinical correlates of polysubstance dependence.

Subjects and methods

Seven hundred and fifty two substance-dependent subjects were interviewed with the Mini-International Neuropsychiatric Interview, the Brown–Goodwin Assessment for Lifetime History of Aggression (BGLHA), and the Hamilton Depression Rating Scale (HDRS). Subjects completed the Childhood Trauma Questionnaire (CTQ), Eysenck Personality Questionnaire (EPQ), and Barratt Impulsivity Scale (BIS). Subjects found to have polysubstance dependence were compared with subjects with monosubstance dependence.


Polysubstance dependence was found in 48.3% of the subjects. Subjects with polysubstance dependence were significantly younger, more were separated/divorced and unemployed, and they had significantly higher CTQ scores for childhood emotional and physical neglect, higher EPQ psychoticism scores, higher BGLHA aggression scores, and higher BIS impulsivity scores. Significantly more of the polysubstance dependent subjects had attempted suicide, self-mutilated, and exhibited aggressive behavior. Significantly more monosubstance dependent subjects had an Axis I psychiatric disorder and they had higher HDRS depression scores.


Polysubstance dependence is common among the groups studied and may be associated with certain socio-demographic, developmental, and personality factors.

  Y Zheng , J Zhu and A. Roy

A powerful technique for inference concerning spatial dependence in a random field is to use spectral methods based on frequency domain analysis. Here we develop a nonparametric Bayesian approach to statistical inference for the spectral density of a random field. We construct a multi-dimensional Bernstein polynomial prior for the spectral density and devise a Markov chain Monte Carlo algorithm to simulate from the posterior of the spectral density. The posterior sampling enables us to obtain a smoothed estimate of the spectral density as well as credible bands at desired levels. Simulation shows that our proposed method is more robust than a parametric approach. For illustration, we analyse a soil data example.

  R.K. Sahu , A. Singh , R. Gupta , A. Roy and J. Dwivedi
  In the present study, it was envisaged to prepare three polyherbal formulations (F1, F2 and F3) containing leaves of Solanum xanthocarpum and Andrographis paniculata, rhizomes of Curcuma longa and stem of Tinospora cordifolia in varying ratio and evaluating the polyherbal formulations for the antipyretic and antinociceptive activities. The antipyretic activity of methanol extracts (MF1, MF2 and MF3) and aqueous extracts (AF1, AF2 and AF3) of polyherbal formulation were studied in Brewer’s yeast induced pyrexia in mice. The antinociceptive activity of methanol and aqueous extracts of polyherbal formulation were studied using Eddy’s hot plate method and tail flick method in mice. The polyherbal formulation of all extracts showed significant reduction in the elevated body temperature of rat which was compared with standard paracetamol. The extract of polyherbal formulation produced significant increase in the reaction time by Eddy’s hot plate method and tail flick method in mice which was compared with standard morphine sulphate. From these results it may be concluded that AF1 formulation demonstrated maximum significant antipyretic and antinociceptive activities that might be due to combined effect of active constituents present in all plant material.
  S. Balamurugan , P. Kannan , K. Yadupati and A. Roy
  We report the synthesis and mesomorphic properties of a homologous series (10a–10g) of bent-core molecules constructed through covalent linkage of structurally non-symmetrical rod-like mesogens connected with a 1, 3-phenylene unit. The study of homologous series underlines the importance of length and nature of terminal chains. The homologues of shorter chains show a typical non-switchable rectangular columnar B1 phase, while the switchable lamellar (B2) phase is induced on moving to higher homologues. X-ray diffraction patterns indicate the presence of B1 and B2 mesophases. Polarised optical microscopy investigations under electric field in the B2 phases revealed the existence of anticlinic antiferroelectric texture. The measured spontaneous polarisation value in one of the compounds is 936 nC cm−2, a high polarisation value in bent-core liquid crystals.
  A. Mandal , G. Rodrigues , D. Kanjilal and A. Roy
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