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Articles by A. Mohammed
Total Records ( 6 ) for A. Mohammed
  S.B. Mada , A. Mohammed , A. Garba , H.A. Mohammed and I. Garba
  The present study was aimed to evaluate the stem bark aqueous extract of Psidium guajava for modulatory effect against CCl4 induced liver damage in rats. A total of thirty six male rats, were randomly divided into six groups of six rats each. The extract was administered orally for 15 days at 125, 250 and 500 mg kg-1 b.wt. The results obtained showed that treatment with the extract significantly (p<0.05) restored liver weight. There was significant (p<0.05) increase in the level of Packed Cell Volume (PCV), haemoglobin (Hb) and Red Blood Cell (RBC) counts and significant (p<0.05) decrease in White Blood Cell (WBC) counts compared to toxin control group. Also administration of the extract caused significant (p<0.05) decrease in the activities of Alanine Transaminase (ALT), Aspartate Transaminase (AST), Alkaline Phosphatase (ALP) and the level of total bilirubin and significant (p<0.05) increase in total protein level compared to toxin control group. Similarly the extract caused a significant (p<0.05) increase in the activities of Catalase (CAT) and Superoxide Dismutase (SOD) and significant (p<0.05) decrease in reduced Glutathione (GSH) and Thiobarbituric Reactive Substances (TBARS) level compared to group 2 (toxin control group). The histopathological study indicated that treatment with the extract restored and regenerated hepatic cells compared to toxin control group. This study found that administration of aqueous stem bark extracts ameliorated hepatotoxicity induced by CCl4 in rats.
  E. Asare-Bediako , A.A. Addo-Quaye and A. Mohammed
  This study was conducted to evaluate the effectiveness of intercropping cabbage with non-host crops in reducing the effect of the diamondback moth pest on cabbage. The experimental design used was a randomized complete block design with five treatments and four replications. The treatments were cabbage-tomato intercrop, cabbage-pepper intercrop, cabbage-onion intercrop, pure cabbage stand sprayed with chlorpyrifos (Dursban) a synthetic insecticide and a pure cabbage stand that was not sprayed (control). Data were taken on plant height, DBM population per plant, leaf damage, head damage and head weight. Cabbage plants intercropped or sprayed with chlorpyrifos against the DBM pests recorded significantly higher growth and yield and less pest damage compared with controls. Intercropping cabbage with onion, tomato or pepper was found to be as effective as spraying the cabbage with chlorpyrifos. Cabbage intercropped with onion and tomato produced lower leaf and head damage and higher yield than those intercropped with pepper.
  A. Mohammed , S.B. Oyeleke and E.C. Egwim
  Fermentable sugars are important prerequisite for ethanol production. These sugars are insufficient for production of the required amount of ethanol for Nigeria consumption in spite availability of raw materials. This study is aimed at producing fermentable sugars by pretreatment and hydrolysis of cassava peels using Aspergillus niger and their crude enzymes (amylase, cellulase and pectinase), as well as comparing the reducing sugar yield. Cassava peels were pretreated by soaking and a combination of soaking and boiling at varying time. Hydrolysis of pretreated cassava peels with Aspergillus niger and crude enzymes were carried out for 5 and 15 days, respectively. The result showed that pretreatment by soaking and boiling for up to 120 min removed the highest amount of cyanide and increased amount of carbohydrate produced but reduced the fibre content (37.04±0.01 mg g-1, 71.42±0.02 and 10.38±0.42%). Hydrolysis using Aspergillus niger yielded up to 95.44±0.11 mg g-1 reducing sugar while hydrolysis using enzymes yielded up to 72.38±0.06 mg g-1 reducing sugar. The study revealed the potentials of cassava peels in reducing sugar production. Soaking and boiling of cassava peels for 120 min removed more cyanide and yielded high carbohydrate needed for reducing sugar production. Microbial cells are better tools that could be used for hydrolysis of carbohydrate to reducing sugars than their enzymatic products.
  A. Mohammed , S.B. Mada and H.M. Yakasai
  Senna siamea is a plant commonly used in traditional medicine to treat hypertension, malaria and diabetes mellitus. The aim of this study was to investigate the sub-chronic toxicity of aqueous extract from the stem bark of S. siamea male Wistar rats. The extract was orally administered for seven weeks at 200, 400, 800 and 1600 mg kg-1 body weight. The results obtained showed that the extract significantly (p<0.05) increases the body weight and feed intake of the rats. Hematological parameters (PCV, Hb, platelets, WBC and RBC) were not significantly (p<0.05) affected by the extract. But the levels of serum liver enzymes (Alkaline Phosphatase (ALP), Alanine Aminotransaminase (ALT), Aspartate Aminotransaminase (AST) were significantly different (p<0.05) from the normal control group. In contrast, no significant change was observed in the total protein and albumin levels in the treated group compared to the normal group. Similarly, serum glucose, triglycerides, cholesterol and the markers of kidney function (creatinine, urea, potassium, sodium and chloride) did not differ significantly (p<0.05) from the normal control group. The quantitative determination of saponins, alkaloids, total polyphenolics and flavonoids in (g/g) were found to be 0.07±0.01, 0.05±0.02, 0.92±0.05 and 0.06±0.01. These results may explain the use of S. siamea stem bark in folk medicine due its less toxic effect.
  N. Bernard , A. Mohammed , A. Edwards and P. Bridgemohan
  Leaf and gel extracts of Aloe barbadense are added to the drinking water in local broiler production to reduce mortality and enhance broiler performance. In this study, 420 day-old chicks (Aber Acres) were randomly divided into 7 groups of 60 chicks of mixed sexes of 20 per replicate (3 replicates per group). The experiment used a 2 x 3 x 3 randomized design with three experimental treatments of either Aloe vera (Aloe barbadense) gel T1, T2, T3, or leaf (T4, T5, or T6) and one control. Across the 42-day grow-out period, there were no significant differences (p>0.05) in feed intake (FI), water consumption (WI), average daily gain (ADG), or feed-conversion ratios (FCR) across treatments. At the end of 21 days, however, the lowest FCR indicator of best performance was found in the T6 20 mL-treated leaf extract group. However, both the 20 mL leaf and 15 mL gel extracts were likely to produce birds of similar weights as traditionally formulated feeds for broilers. Therefore, poultry producers should include a moderate level of Aloe vera gel and the highest leaf extracts in the drinking water, as these extracts may prove to be more cost effective than manufactured feeds for optimal broiler performance. It may also be more cost effective for the poultry producer to use the 20 mL leaf and gel extracts as a means of reducing overall mortality. The finding that compounds in Aloe vera foster less bone deposition and greater muscle accretion in female broilers warrants further investigation.
  N. Wanmi , A. Mohammed and T. Nev
  Parrot population in Africa is declining and the need for conservation actions to address threats is increasingly recognized. The situation is worst in Nigeria and if care is not taken, this species of bird will soon go into instinct. The essence of this study was to obtain a data base of some body organs of the wild Senegal parrot which are scarce. Documentation on this species of bird is rare despite they are being hunted for because of its demand as ornamental bird. The mean weights (whole body, gastrointestinal tract (GIT)+content and GIT empty) were observed to be 120.50±5.42, 18.01±4.80 and 13.54±5.51 g, respectively. The liver had mean weight of 4.18±1.82 while the tongue, lower respiratory system (LRS), heart and kidney were observed to be, 2.76±2.14 g, 5.83±1.65, 1.81±0.65 and 0.41±0.05 g. The mean length (whole body+tail) were observed to be 9.85±1.20 cm. The mean lengths (GIT, liver tongue and LRS) were 82.62±2.36, 4.33±1.82, 2.04±0.99 and 12.69±2.10 cm with GIT and LRS accounting for 76.93 and 19.97%. The syrinx is very large suggesting sound production is pronounced and the large intestine is void of cecum.
 
 
 
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