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Articles by A. Geetha
Total Records ( 4 ) for A. Geetha
  P. Samudram , H. Rajeshwari , R. Vasuki , A. Geetha and P. Sathiya Moorthi
  The combined hepatoprotective effect of Bi-Herbal Ethanolic Extract (BHEE) pretreatment against carbon tetra chloride (CCl4) induced hepatic damage in rats was investigated. Ethanolic extract from the leaves of Melia azedarach and seeds of Piper longum at a dose level of 50 mg kg-1 body weight was administered orally daily once for 14 days, prior to the administration of 0.2 mL of CCl4 kg-1 body weight for 7 days. The substantially elevated serum marker enzymes such as Serum glutamic Oxaloacetic Transaminase (SGOT), Serum Glutamic Pyruvic Transaminase (SGPT), Alkaline Phosphatase (ALP), Acid Phosphatase (ACP), Lactatedehydrogenase (LDH), Gamma glutamyl Transferase (γGT) and 5 Nucleotidase (5NT), due to CCl4 treatment were restored towards normalization in rats pretreated with BHEE. The determination of liver weight and biochemical parameters such as serum bilirubin and blood urea showed a remarkable decrease in rats pre- treated with the BHEE when compared with those administered CCl4 alone. In addition BHEE significantly increased the total protein, total cholesterol and triglyceride also towards normal levels. Silymarin at a dose level of 50 mg kg-1 was used as a standard reference also exhibited significant hepatoprotective activity against CCl4 induced hepatotoxicity. The results of this study strongly indicate that BHEE has got a potent hepatoprotective action against CCl4 induced hepatic damage in rats.
  A. Geetha and P. Perumal
  This study deals, the durability and strength of concrete using admixtures. This addition of water proofing admixtures turns concrete into a construction material in harmony with sustainable building development. The addition of water proofing admixtures also increases the various strength of concrete. These studies were carried out by conducting tensile, compressive and flexural strength tests of the concrete specimen with and without admixtures for various dosages and various curing periods of 7 and 28 days. For flexural strength concrete prism of size 100x100x500 mm, for compression test cube of 150x150x150 mm, for split tensile test cylinders of 150x300 mm. For durability study permeability tests were conducted on the cube specimen of size 150x150x150 mm. The results showed that the presence of waterproofing admixtures always improves the corrosion resistance and thus, increases the strength of concrete.
  R. Sangeetha , I. Arulpandi and A. Geetha
  Lipases are hydrolytic enzymes which hydrolyse triglycerides to free fatty acids and glycerol. These enzymes also catalyse transesterification, aminolysis and acidolysis reactions. Their potential to function in non-aqueous and micro-aqueous environments makes them a versatile biotechnological tool. Lipases are ubiquitous in nature and those from microbes have occupied a prominent position as industrial biocatalysts. Both fungal and bacterial lipases have been exploited by various industries. The chemo, regio and enantio-selectivity of lipases are properties which widen their range of industrial applications. This review was aimed at providing a collective knowledge about bacterial lipases and this article discusses the fundamental details about the sources and cellular location of lipase and the production and purification of the enzyme. Immobilisation and bioimprinting techniques which improve the catalytic efficacy of lipase have also been discussed. This overview also enumerates and describes briefly the extensive applications of bacterial lipases.
  R. Palani and A. Geetha
  Density (ρ), viscosity (η) and ultrasonic velocity (U) have been measured at 298.15 K in aqueous D-glucose solutions ranging from pure water to 40 mass % of D-glucose. These measurements have been performed to evaluate some important parameters viz. Adiabatic compressibility (β), molar hydration number (nH), apparent molar compressibility (φk) apparent molar volume (φV), limiting apparent molar compressibility , limiting apparent molar volume and their constants (SK, SV), transfer partial molar volume and viscosity A and B coefficient of Jones-Dole equation. These parameters have been interpreted the molecular interactions in terms of solute-co-solute and solute-solvent interaction present in the given solutions.
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