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Articles by A. Ferrara
Total Records ( 2 ) for A. Ferrara
  S. F. Ehrlich , M. M. Hedderson , C. P. Quesenberry Jr , J. Feng , S. D. Brown , Y. Crites and A. Ferrara
 

Aims

Women with gestational diabetes are at high risk for developing diabetes; post-partum weight loss may reduce the risk of diabetes. We evaluated the association of post-partum weight change with changes in glucose, insulin and homeostasis model assessment of insulin resistance in a subsample (n = 72) of participants from Diet Exercise and Breastfeeding Intervention (DEBI), a randomized pilot trial of lifestyle intervention for women with gestational diabetes.

Methods

Glucose and insulin were measured fasting and 2 h after an oral glucose tolerance test at 6 weeks and 12 months post-partum. Women were categorized by weight change (lost > 2 kg vs. maintained/gained) between 6 weeks and 12 months post-partum.

Results

Compared with women who maintained or gained weight, women who lost > 2 kg experienced significantly lower increases in fasting glucose [age-adjusted means: 0.1 mmol/l (95% CI -0.03 to 0.3) vs. 0.4 mmol/l (95% CI 0.3-0.6); < 0.01] and 2-h insulin [10.0 pmol/l (95% CI -56.9 to 76.9) vs. 181.2 pmol/l (95% CI 108.3-506.9); < 0.01] and a significant reduction in 2-h glucose [-0.9 mmol/l (95% CI -1.4 to -0.3) vs. 0.3 mmol/l (95% CI -0.3 to 0.9); < 0.01]. In multiple linear regression models adjusted for age, Hispanic ethnicity, medication use, meeting the Institute of Medicine's recommendations for gestational weight gain, breastfeeding and randomized group, a 1-kg increase in weight was significantly associated with increases in fasting and 2-h glucose (P < 0.05), but was not associated with insulin or homeostasis model assessment of insulin resistance.

Conclusions

In women with gestational diabetes, modest post-partum weight loss may be associated with improvements in glucose metabolism.

  A. Ferrara , S. Lovelli , T. Di Tommaso and M. Perniola
  In this study, the effects of water stress at different growth stages on dynamics of flowering and fruit production of greenhouse grown pepper plants were investigated. Irrigation treatments included complete restoration of water use during the whole growing season (control), water deficit during the vegetative phase (vegetative stressed stage) and water deficit during the reproductive phase (reproductive stressed stage). Soil water content was periodically measured; leaf water and osmotic potential, net assimilation rate, stomatal conductance, transpiration rate, intercellular CO2 concentration were also measured on pepper leaves. Flowers were monitored till the end of the crop cycle to calculate fruit setting. Leaf water and osmotic potential changed with time according to the soil water content of stressed treatments. Photosynthesis was lower in vegetative stressed stage and reproductive stressed stage treatments during the water stress periods compared to the well watered control. During the vegetative phase, water stress significantly reduced the number of flowers per plant, decreasing from 30.9 to 10.7 in the control and vegetative stressed stage treatments, respectively. Unlike flowering, setting was not affected by water stress, when it was imposed during both the vegetative and reproductive phases. Total pepper yield gradually decreased going from the fully irrigated treatment to the treatment stressed during the vegetative phase, getting to the lowest value in the treatment stressed during the reproductive phase (5644, 2040 and 875 g m-2, respectively). Since setting was not affected by water stress, the attention on irrigation scheduling should not be paid only on reproductive phase, but on the whole growing cycle.
 
 
 
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