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Articles by A. Amin
Total Records ( 2 ) for A. Amin
  A. H. Sam , M. Busbridge , A. Amin , L. Webber , D. White , S. Franks , N. M. Martin , M. Sleeth , N. A. Ismail , N. Mat Daud , D. Papamargaritis , C. W. Le Roux , R. S. Chapman , G. Frost , S. R. Bloom and K. G. Murphy
 

Aim

Increased body iron is associated with insulin resistance. Hepcidin is the key hormone that negatively regulates iron homeostasis. We hypothesized that individuals with insulin resistance have inadequate hepcidin levels for their iron load.

Methods

Serum concentrations of the active form of hepcidin (hepcidin-25) and hepcidin:ferritin ratio were evaluated in participants with Type 2 diabetes (n = 33, control subjects matched for age, gender and BMI, n = 33) and participants with polycystic ovary syndrome (n = 27, control subjects matched for age and BMI, n = 16). To investigate whether any changes observed were associated with insulin resistance rather than insulin deficiency or hyperglycaemia per se, the same measurements were made in participants with Type 1 diabetes (n = 28, control subjects matched for age, gender and BMI, n = 30). Finally, the relationship between homeostasis model assessment of insulin resistance and serum hepcidin:ferritin ratio was explored in overweight or obese participants without diabetes (n = 16).

Results

Participants with Type 2 diabetes had significantly lower hepcidin and hepcidin:ferritin ratio than control subjects (< 0.05 and < 0.01, respectively). Participants with polycystic ovary syndrome had a significantly lower hepcidin:ferritin ratio than control subjects (< 0.05). There was no significant difference in hepcidin or hepcidin:ferritin ratio between participants with Type 1 diabetes and control subjects (= 0.88 and = 0.94). Serum hepcidin:ferritin ratio inversely correlated with homeostasis model assessment of insulin resistance (r = -0.59, P < 0.05).

Conclusion

Insulin resistance, but not insulin deficiency or hyperglycaemia per se, is associated with inadequate hepcidin levels. Reduced hepcidin concentrations may cause increased body iron stores in insulin-resistant states.

  M.M. Rahman , M.A. Awal , A. Amin and M.R. Parvej
  An experiment was conducted to analyse the interspecies compatibility and production potentials of mustard and lentil in intercrop association. The experiment comprised four planting systems viz., sole mustard, sole lentil, single row (1:1 i.e., one row of mustard followed by one row of lentil) and double row (1:2 i.e., one row of mustard followed by two rows of lentil) intercropping. The stands height and number of branches (primary and secondary) per plant were maximum and minimum in sole and single row intercropped plants, respectively. Higher leaf area index and total dry matter production was observed in sole cropped mustard or lentil while those were lower in 1:2 intercropped mustard or 1:1 intercropped lentil plants. Maximum seed yield, 1.26 t ha-1 (or 1.30 t ha-1) was harvested from sole crop of mustard (or lentil) which was about 40 and 48% (or 34 and 12%) higher than that of the mustard (or lentil) yield obtained from single and double row intercrop mixtures, respectively. Combined seed yield from double row mixture was the maximum (1.8 t ha-1) and was respectively 11, 30 or 28% higher than that obtained from single row intercropped stands, sole mustard or lentil. Single and double row intercropping systems respectively resulted 25 or 41% increase in land equivalent ratios. Area time equivalency ratio was also increased by about 14 and 31%, respectively for single and double row intercropping systems. The competitive ratio of each population is approached to be unity in both intercropping systems reflecting the proper balance of the natural resources between associated species resulted better yield. The results suggest that mustard and lentil populations are well compatible in intercrop association and 1:2 row ratio mixture would be better for their profitable production.
 
 
 
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