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Articles by A. Abdullahi
Total Records ( 3 ) for A. Abdullahi
  I.O. Obaroh , J.N. Keta , J. Nwaogu and A. Abdullahi
  Background and Objective: The use of phytoadditives in fish culture is on the rise due to their greater advantages over the synthetics drugs. Moringa oleifera saponins has a positive effect on fish growth, however little is known about its effects on liver and intestine. Thus, this study was aimed at investigating the effects of crude extract of Moringa oleifera saponin on liver and intestine histology of Clarias gariepinus. Materials and Methods: Crude saponins were isolated from Moringa oleifera leaf using standard procedures. Two hundred and forty fish divided into 4 groups (A, B, C and D) and fed for 60 days with varying concentrations of the crude extract (0.0, 0.5, 1.0 and 1.5 g kg1) incorporated into basal diet. At the end of the study, liver and intestines from fish in each group were sectioned using standard procedure. Results: Photomicrograph impression of the fish liver in the control group revealed normal central vein and fats cells. While in the other groups deposit of fat cells distorting the normal architecture of the liver and fibrosis were observed as the concentration of saponin increases. The intestine of fish in the control group revealed normal mucosal lining. While in the other groups normal mucosal lining and gradual increase in the number of inflammatory cells in submucosa were observed as the concentration of saponins increases. Conclusion: This study infers that crude extract of Moringa oleifera saponins affects the structure of the liver and causes inflammation in the intestine of Clarias gariepinus especially at high concentrations.
  S.F. Ambali , A.T. Abubakar , M. Shittu , L.S. Yaqub , S.B. Anafi and A. Abdullahi
  Chlorpyrifos (CPF) toxicity has been shown to be partly mediated through induction of oxidative stress. In the present study, experiments were conducted with the aim of evaluating the ameliorative potentials of zinc on CPF-evoked alteration in hematological parameters in Wistar rats. Twenty adult male Wistar rats were divided at random into 4 groups of 5 animals per group. Rats in group I served as the control and were given only soya oil (2 mL kg-1) while those in group II were administered zinc only (50 mg kg-1). Rats in group III were dosed with CPF only (10.6 mg kg-1, ~1/8th of LD50). Those in group IV were co-administered zinc (50 mg kg-1) and CPF (10.6 mg kg-1). The different regimens were administered orally once daily for a period of 8 weeks. At the end of the study period, blood samples collected after sacrificing the animals were analyzed for hematologic parameters such as Packed Cell Volume (PCV), Hemoglobin (Hb), Red Blood Cells (RBC), Mean Cell Volume (MCV), Mean Corpuscular Hemoglobin (MCH), Mean Corpuscular Hemoglobin Concentration (MCHC), hemoglobin indices, platelets, absolute and differential White Blood Cell (WBC) counts, neutrophil-lymphocyte ratio and erythrocyte malonaldehyde (MDA) concentration. The results revealed that alterations in the values of PCV, Hb, RBC, platelets, absolute and differential WBC and MDA induced by CPF were ameliorated by co-administration with zinc. In conclusion, the study has shown that attenuations of CPF-evoked alterations in hematological parameters by zinc may be partly mediated through its antioxidant properties.
  M.U. Kawu , L.S. Yaqub , J.O. Ayo , P.I. Rekwot , B. Habibu , M. Tauheed , M.M. Suleiman , M. Shittu , T. Aluwong , H.I. Isa and A. Abdullahi
  The aim of this study was to evaluate the features of induced abortion and post-abortion oestrous cycles pattern following treatment with prostaglandin F (PGF) in Sokoto Red (SR) goats. Twelve apparently healthy goats made up of 6 pregnant and 6 non-pregnant (cycling) does were used for the study. Each doe was given a single intramuscular injection of 7.5 mg PGF. All the 6 pregnant does treated with PGF aborted within 72.0±12.4 h post-treatment. Of the 6 does that aborted, 5 (83.3%) showed oestrus subsequently while 4 (66.7%) out of the 6 non-pregnant does were induced to oestrus. Time interval to induced oestrus was 129.6±36.1 and 50.0±11.5 h for the aborted and non-pregnant does, respectively. Mean duration of oestrus for the aborted and non-pregnant does was 46.9±9.6 and 38.7±4.3 h, respectively. The first and second post-abortion oestrous cycle lengths were 6.5±0.5 and 12.5±8.5 days, respectively. While the first and second post-treatment cycle lengths in the non-pregnant does was 22.5±1.2 and 21.3±0.3 days, respectively. It is concluded that a single dose of 7.5 mg PGF is sufficient to induce abortion and oestrus simultaneously in SR goats. However, the post-abortion cycles are short.
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