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Articles by A. Safameher
Total Records ( 2 ) for A. Safameher
  A. Safameher
  This study was conducted to determine performance and biochemical and histopathological changes in Chicks that Clinoptilolite (CLI) was added to diets containing Aflatoxins (AF) from 1-42 days of age. A total of 480, One-day-old broiler chicks (Ross 308) was divided into 6 treatments: control; basal diet prepared with uncontaminated diet, control containing AF (0.5 mg kg 1), control containing AF (1 mg kg 1), control containing CLI (20 g kg 1), control containing AF (0.5 mg kg 1) + CLI (20 g kg 1) and control containing AF (1 mg kg 1) + CLI (20 g kg 1) ) each consisting of 80 chicks. Chickens were monitored daily and then body weight and feed consumption were recorded. Plasma enzymatic and non-enzymatic parameters showed progressive changes in birds examined 21 or 42 days after dietary aflatoxin treatments. Compared to controls, the AF treatment significantly (p<0.05) decreased body weight gain, feed intake, serum total protein, albumin, cholesterol, uric acid, calcium, phosphorus, alkaline phosphatase (ALP) and from enzymatic parameters Lactate Dehydrogenase (LDH) and aspartate amino transferase (AST) increased. Decreases in serum parameters caused by AF was significantly (p<0.05) ameliorated by CLI. A similar increase was obtained in feed intake and body weight gain by adding CLI to the AF-containing diet (p<0.05). Histopathologic examination revealed severe fatty change, regeneration foci of liver cells, fibrosis of portal regions and bile ductule hyperplasia. The addition of CLI to the AF-containing diet decreased the severity of lesions (hepatic lipidosis, regeneration foci and bile-duct hyperplasia) in the livers. Prolonged exposure to low concentration of the toxin produce severe changes in fat metabolism and bile ductule proliferation. These results suggest that CLI (20 g kg 1) was effective for the protection of AF-toxication in broiler chicks and addition of CLI effectively diminished the detrimental effects of AF on traits investigated.
  A. Safameher and M. Shivazad
  The amelioration of aflatoxicosis in broiler chicks was examined by the dietary addition of Saccharomyces Cerevisiae (SCE). Saccharomyces cerevisiae incorporated into the diet at 1 g kg 1 was evaluated for its ability to reduce the deleterious effects of 1 and 2 ppm Aflatoxins (AF) on Ross broiler chicks from 1days to 42 days of age. The AF treatments significantly decreased feed consumption and body-weight gain and increased feed conversion ratio (p< 0.05). Serum cholestrol, total protein and albumin decreased significantly (p< 0.05) in diets contaminated with aflatoxin. Compared to controls, the addition of SCE to an AF-containing diet significantly reduced the deleterious effects of AF on body-weight gain, feed conversion ratio, cholestrol, albumin and total protein. The AF fed groups had higher serum activities of the enzymes LDH and AST and decreased activity of ALP. The addition of SCE to an AF-containing diet reversed the effect of the toxin on the activities of serum enzymes. These results suggest that SCE reduced the adverse effects of AF and should be helpful in a solution to the aflatoxicosis problem in poultry.
 
 
 
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