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Articles by A. Okorie Domingo
Total Records ( 2 ) for A. Okorie Domingo
  A. Aladedunye Felix and A. Okorie Domingo
  The plant, Culcasia scandens P. Beauv. is popularly used in the treatment of tonsillitis, toothache and other inflammatory conditions in the southern part of Nigeria. The hexane, ethyl acetate and methanol extracts of this plant was evaluated for antimicrobial activity against Escherichia coli, Bacillus subtilis, Pseudomonas aeruginosa, Candida albicans, Trichophyton mentagrophytes and Cladosporium resinae. All the extracts examined showed no activity. Phytochemical analysis of the extracts however, revealed the presence of homologous very-long-chain 1,3-alkanediols, homologous series of C31, C33 and C35 alkanols, protoquercitol, methyl -D-fructopyranoside, palmitic acid, stearic acid, linoleic acid, linolenic acid and their methyl esters.
  A. Aladedunye Felix and A. Okorie Domingo
  Phytochemical analysis of foliage of Pupalia lappacea (L.) Juss (Amaranthaceae) afforded 8 compounds, namely; 1-docosanol, stearic acid, stigmasterol, -sitosterol, N-benzoyl-L-phenylalaninol acetate, -sitosterol-3-O- -D-glucopyranoside, stigmasterol-3-O- -D-glucopyranoside and 20-hydroxyecdysone. The ecdysteroid, 20-hydroxyecdysone, constitutes nearly 0.3% of the dry weight and 13% of the dichloromethane extracts of the plant, making Pupalia lappacea a probable commercial source for this important ecdysteroid. Both the hexane and dichloromethane extracts showed significant antioxidant activity with the dichloromethane exhibiting an IC50 comparable to that of BHT, a synthetic antioxidant. All the isolated compounds are reported for the first time in the genus.
 
 
 
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