Slow Binding Inhibition and Mechanism of Resistance of Non-nucleoside Polymerase Inhibitors of Hepatitis C Virus

J. Q Hang, Y Yang, S. F Harris, V Leveque, H. J Whittington, S Rajyaguru, G Ao Ieong, M. F McCown, A Wong, A. M Giannetti, S Le Pogam, F Talamas, N Cammack, I Najera and K. Klumpp

The Journal of Biological Chemistry 284 ( 23 ): 15517 - 15529 , 2009