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Articles by A. Karimi Nik
Total Records ( 2 ) for A. Karimi Nik
  G.H. Shahidi Bonjar and A. Karimi Nik
  Increase of antibacterial resistance is a global growing-problem. Isolation of microbial agents less susceptible to regular antibiotics and recovery of increasing resistant isolates during antibacterial therapy is rising throughout the world which highlights the need for new principles. In treating burns, dermatophytes and infectious diseases, use of plants is common in traditional medicine of Iran. According to the collected information about herbal remedies of such plants, antibacterial activities of methanol extracts of the plants were determined by in vitro bioassays using agar diffusion-method against standard strains of Pseudomonas aeruginosa and P. fluorescens at 20 mg ml-1. From 160 plant species in 65 families, 13 species (8.1%) in 12 families (18.4%) showed anti-Pseudomona activities. Activities included 6.2% against P. aeruginosa and 7.5% against P. fluorescens. Minimum inhibitory concentrations (MIC) of the actives were determined using two fold serial dilutions. Most active plants against both bacterial species were Dianthus caryophyllus L., Terminalia chebula (Gaertner) Retz. and Myrtus communis L. with the MIC of 3.75, 1.87 and 7.5 mg ml-1 against P. aeruginosa; 0.46, 0.93 and 1.87 mg ml-1 against P. fluorescens, respectively.
  G.H. Shahidi Bonjar , S. Aghighi and A. Karimi Nik
  Methanol plant-extracts of 221 species from 98 families which had documented uses in Iranian herbal-medicine were screened for antibacterial and antifungal activity against 11 standard bacterial strains and 3 fungal species at 20 mg mlG1. Eighty one samples in 39 families showed antibacterial and/or antifungal activity against at least on one of the tested microorganisms. Antimicrobial activities were evaluated by measuring the diameter of inhibition zones in agar well diffusion method. Dianthus coryophyllus was active against all tested G-ve and G+ve bacteria except Micrococcus luteus. Most susceptible G-ve bacteria were Klebsiella pneumoniae and Bordetella bronchiseptica and least susceptible was Escherichia coli. In G+ve bacteria, most and least susceptible were Staphylococcus aureus and Micrococcus luteus, respectively. Plants with high antifungal activity included Alpinia officinarum, Chrozophora verbasafalia, Cinnamomum zeylanicum, Dianthus coryophyllus, Helleborus nigra, Heracleum persicum, Myrtus communis, Terminalia chebula and Trachysermum copticum which were effective mostly against Candida albicans and C. utilis.
 
 
 
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