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Veterinary Research
Year: 2008  |  Volume: 2  |  Issue: 2  |  Page No.: 25 - 27

The Effect of Crude Methanolic Extracts of Mitracarpus scaber on Dermatophilus congolensis

J. Imam, B.I. Onyeanusi, U.S. Abdullahi, S.O. Salami, J.O. Nzalak, M.B. Umar, A.D. Umosen, S.M. Maidawa, M.N. Ali, M.M. Suleiman and O. Byanet    

Abstract: Mitracarpus scaber is a local herb traditionally used for the treatment of eczema and other skin disorders. Methanolic extracts made from leaves, stem, fluorescence and roots were prepared and dried. Graded concentrations of the 4 separate plant parts were prepared in nutrient broth contained in universal bottles at 10, 7, 5, 3 and 2 g mL 1. Standard chloramphenicol (Norbrook Laboratories Ltd., London) was similarly prepared and used as known antibiotic. An isolate of Dermatophilus congolensis was obtained and inoculated in each of the graded broth media and incubated at 37C, microaerophilically, for 24 h. Two replications were made with blank controls and growth of Dermatophilus congolensis was observed and recorded. The results obtained showed that leaves, fluorescence and root extracts were inhibitory at concentration of 3 g mL 1 while, stem extract was at 5 g mL 1. Chloramphenicol was inhibitory at 2 g mL 1. It is recommended that research be carried out on this plant to further elucidate its antimicrobial potentials.

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