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Trends in Medical Research

Year: 2009  |  Volume: 4  |  Issue: 1  |  Page No.: 1 - 7

Histopathological Patterns of the Testes in Patients with Severe Burns Not Involving the Perineum (A Case Series Study)

I.O. Fadeyibi, L.C. Saalu, P.I. Jewo, A.S. Benebo and S.A. Ademiluyi


The aim of this study is to investigate the histopathological features of the testis of Burns patients where the burns did not involve the perineum. The present study is a case series report of the testicular histopathological changes of adult patients that died from major burns not involving the perineum. All adult male patients that sustained major burns, were managed at Lagos State University Teaching Hospital (LASUTH) and satisfied the inclusion criteria were recruited into the study. Testicular specimens were obtained during the routine postmortem examinations of patients that died from burns. Histological evaluation of the testes was done by light microscopy. There was mild to moderate testicular interstitial oedema with markedly reduced Leydig and Sertoli cells. Cells of the Spermatogenic series were present and of normal appearances. However, cells of the Spermiogenic series were scanty and no mature spermatozoon was observed. These findings show that major burns result in indirect derangement in the testicular morphology.

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