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Trends in Medical Research

Year: 2007  |  Volume: 2  |  Issue: 1  |  Page No.: 37 - 43

Evaluation of Antioxidants Effect of Citrus reticulata in Schistosoma mansoni Infected Mice

Hanan F. Ali

Abstract

The antioxidant activity of flavonoid contents of Citrus reticulata. Baladi roots cultivated in Egypt, Family Rutaceae has been evaluated in six groups of healthy and infected mice with Schistosoma mansoni. Evaluation of the results was accomplished using a standard drug, Mirazid. Several antioxidant parameters were tested: lipid peroxide, glutathione (GSH), vitamin C (Vit C) and E (Vit E), catalase enzyme and liver function enzymes. Schistosoma mansoni infection showed a drastic changes of all the parameters under investigation. Treatment with Citrus reticulata and Mirazid showed amelioration in the hepatic antioxidant parameters; LP, GSH, Vit. C, Vit. E, Catalase enzyme as well as liver function enzymes; aspartate and alanine aminotransferases (AST and ALT) and alkaline phosphatase (ALP).

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