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Trends in Applied Sciences Research
Year: 2019  |  Volume: 14  |  Issue: 3  |  Page No.: 199 - 204

Antioxidant Activities of Asparagus adscendens Root Ethanolic Extract and Fractions Using in vitro Models

Rita Maneju Sunday, Efere Martins Obuotor and Anil Kumar    

Abstract: Background and Objective: The Asparagus adscendens root is used in ayurvedic medicine for the treatment of various diseases. In this study, the antioxidant properties of Asparagus adscendens root ethanolic extract and extract fractions (n-butanol, ethyl acetate and n-hexane) were investigated using in vitro models. Materials and Methods: The antioxidant activities were determined by 2, 2-Diphenyl-1-picrylhydrazyl, hydrogen peroxide and nitric oxide radical scavenging assays. The total antioxidant capacity, total flavonoid and total phenol content of the extracts were evaluated by spectrophotometric method. Results: The ethanolic extract and extract fractions exerted potent radical scavenging activities. Ethyl acetate extract fraction at 62.5 μg had the highest 2, 2-Diphenyl-1-picrylhydrazyl (77.87%), hydrogen peroxide (56.63%) and nitric oxide (56.28%) radical scavenging activity when compared with the ethanolic extract and other extract fractions. Flavonoids and phenols were also present in the ethanolic extract and extract fractions. The ethyl acetate extract fraction showed a higher total flavonoid content (29.9 mg quercetin equivalent/g of extract), total phenol content (47.9 mg gallic acid equivalent/g of extract) and total antioxidant capacity (35.9 mg ascorbic acid equivalent/g of extract) when compared with the ethanolic extract and other extract fractions. Conclusion: The results of this research indicated that Asparagus adscendens root ethyl acetate extract fraction have high antioxidant potentials and could be explored as a therapeutic agent for the treatment of free radical induced diseases.

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