Abstract: Biochemical studies with a view to assess the nutritional potentials of Anisopus mannii were carried out by evaluating the proximate composition, mineral elements and anti-nutritional content of the plant. The results showed that the total oxalates, free cyanides, tannins and total cyanides were found to be present at 0.70 ± 0.5, 6.50 ± 0.41, 10.55 ± 0.01 and 12.41 ± 7.19%, respectively. However, concentration of phytate was very low (0.017 ± 0.00%). Proximate compositions of the plant showed a rich source of crude protein (8.40 ± 0.17%), fats (8.67 ± 0.63%), carbohydrates (72.57 ± 0.68%) and total ash (10.36 ± 0.22%). The plant was also found to contain the following essential minerals: potassium (1700 mg/100 g), calcium (1280 mg/100 g), iron (156 mg/100 g), vanadium (102 mg/100 g), chromium (53.90 mg/100 g), zinc (0.874 mg/100 g), copper (1.43 mg/100 g) and manganese (36.60 mg/100 g). The results of this research indicated that Anisopus mannii has nutritional qualities that could provide the users with additional nutrients for enhanced curative process of ill health.