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Research Journal of Pharmacology
Year: 2007  |  Volume: 1  |  Issue: 1  |  Page No.: 9 - 11

Quality Control Assay of Ampicillin Brands of Capsules in Onitsha Market, Southeastern Nigeria

I.A. Okoro and E.N. Ejike    

Abstract: The ampicillin content (5) if ten different brands of ampicillin capsules in circulation in the onitsha central drug market were determined. Two analytical methods were used; iodiometric and UV-visible spectrophotometric analyses. The results showed that 60% of the different brands of capsules analyzed were within Bp stipulation values where as 40% of the remaining brands of capsules were blow the Bp stipulated values. Two brands; miracillin and polfa brands of ampicillin capsules were completely out of the range of stipulated values. These two brands are therefore, substandard, adulterated and the prevalence of fake, adulterated and substandard ampicillin capsules in this market is a great damager to the health of the entire people of West Africa sub region that depend entirely on this market for their pharmaceuticals.

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